Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 5 studies | 21% ± 7% |
Insufficient scRNA-seq data for expression of ATAD3A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1445.05 | 1445 / 1445 | 100% | 33.75 | 183 / 183 |
uterus | 100% | 1209.65 | 170 / 170 | 100% | 47.74 | 459 / 459 |
thymus | 100% | 1364.48 | 653 / 653 | 100% | 22.48 | 603 / 605 |
brain | 100% | 951.97 | 2632 / 2642 | 100% | 27.27 | 704 / 705 |
prostate | 100% | 1482.89 | 245 / 245 | 99% | 27.52 | 498 / 502 |
skin | 100% | 1891.12 | 1809 / 1809 | 99% | 52.41 | 468 / 472 |
ovary | 100% | 998.56 | 180 / 180 | 99% | 25.45 | 426 / 430 |
pancreas | 100% | 1168.44 | 328 / 328 | 99% | 24.39 | 176 / 178 |
intestine | 100% | 1250.43 | 966 / 966 | 99% | 43.90 | 521 / 527 |
bladder | 100% | 1391.86 | 21 / 21 | 99% | 43.85 | 497 / 504 |
stomach | 100% | 1118.99 | 359 / 359 | 99% | 37.03 | 282 / 286 |
liver | 100% | 1454.08 | 226 / 226 | 98% | 19.47 | 399 / 406 |
lung | 100% | 1298.66 | 576 / 578 | 98% | 29.21 | 1134 / 1155 |
kidney | 100% | 1273.91 | 89 / 89 | 96% | 15.69 | 866 / 901 |
breast | 100% | 1267.68 | 459 / 459 | 96% | 23.67 | 1072 / 1118 |
adrenal gland | 100% | 1734.67 | 258 / 258 | 96% | 16.26 | 220 / 230 |
eye | 0% | 0 | 0 / 0 | 100% | 56.09 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 47.63 | 29 / 29 |
muscle | 100% | 1662.20 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1570.82 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 44.54 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 30.70 | 1 / 1 |
adipose | 100% | 1218.99 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 940.23 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 1119.25 | 851 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 85% | 935.97 | 791 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0140468 | Biological process | HRI-mediated signaling |
GO_0006974 | Biological process | DNA damage response |
GO_0007005 | Biological process | mitochondrion organization |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0140374 | Biological process | antiviral innate immune response |
GO_0001558 | Biological process | regulation of cell growth |
GO_0042645 | Cellular component | mitochondrial nucleoid |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | ATAD3A |
Protein name | ATPase family AAA domain containing 3A ATPase family AAA domain-containing protein 3A |
Synonyms | |
Description | FUNCTION: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. Involved in mitochondrial-mediated antiviral innate immunity . . |
Accessions | ENST00000400830.4 Q9NVI7 H0Y2W2 Q5SV16 ENST00000339113.9 ENST00000536055.6 [Q9NVI7-3] ENST00000378755.9 [Q9NVI7-1] ENST00000378756.8 [Q9NVI7-2] |