ATAD3A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATAD3A at tissue level.

III. Associated gene sets

GO_0140468Biological processHRI-mediated signaling
GO_0006974Biological processDNA damage response
GO_0007005Biological processmitochondrion organization
GO_0043066Biological processnegative regulation of apoptotic process
GO_0140374Biological processantiviral innate immune response
GO_0001558Biological processregulation of cell growth
GO_0042645Cellular componentmitochondrial nucleoid
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameATAD3A
Protein nameATPase family AAA domain containing 3A
ATPase family AAA domain-containing protein 3A
Synonyms
DescriptionFUNCTION: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. Involved in mitochondrial-mediated antiviral innate immunity . .

AccessionsENST00000400830.4
Q9NVI7
H0Y2W2
Q5SV16
ENST00000339113.9
ENST00000536055.6 [Q9NVI7-3]
ENST00000378755.9 [Q9NVI7-1]
ENST00000378756.8 [Q9NVI7-2]