I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 16 studies | 41% ± 16% | |
| epithelial cell of proximal tubule | 3 studies | 23% ± 4% | |
| fibroblast | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 16 studies | 41% ± 16% | |
| epithelial cell of proximal tubule | 3 studies | 23% ± 4% | |
| fibroblast | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 26% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 2353.16 | 89 / 89 | 85% | 24.44 | 769 / 901 |
| brain | 98% | 2947.79 | 2589 / 2642 | 87% | 10.79 | 610 / 705 |
| skin | 66% | 430.40 | 1193 / 1809 | 57% | 5.74 | 268 / 472 |
| prostate | 87% | 904.10 | 212 / 245 | 17% | 0.59 | 84 / 502 |
| bladder | 95% | 1057.05 | 20 / 21 | 7% | 0.29 | 36 / 504 |
| uterus | 96% | 1242.37 | 163 / 170 | 6% | 0.28 | 27 / 459 |
| adrenal gland | 81% | 579.40 | 208 / 258 | 18% | 0.76 | 42 / 230 |
| breast | 89% | 1016.40 | 409 / 459 | 9% | 0.28 | 96 / 1118 |
| intestine | 93% | 1075.52 | 897 / 966 | 3% | 0.16 | 17 / 527 |
| lung | 89% | 831.85 | 513 / 578 | 6% | 0.20 | 68 / 1155 |
| adipose | 95% | 1404.57 | 1138 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 94% | 939.31 | 227 / 241 | 0% | 0 | 0 / 0 |
| liver | 73% | 710.91 | 164 / 226 | 20% | 0.87 | 82 / 406 |
| stomach | 75% | 525.71 | 268 / 359 | 7% | 0.26 | 20 / 286 |
| thymus | 75% | 501.48 | 493 / 653 | 4% | 0.20 | 24 / 605 |
| esophagus | 71% | 761.63 | 1033 / 1445 | 6% | 0.20 | 11 / 183 |
| ovary | 72% | 630.19 | 130 / 180 | 1% | 0.07 | 3 / 430 |
| muscle | 67% | 579.91 | 541 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 51% | 3.80 | 41 / 80 |
| heart | 40% | 270.25 | 342 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 9% | 39.89 | 30 / 328 | 24% | 0.87 | 42 / 178 |
| blood vessel | 28% | 197.46 | 368 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 2.43 | 5 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006083 | Biological process | acetate metabolic process |
| GO_0048714 | Biological process | positive regulation of oligodendrocyte differentiation |
| GO_0022010 | Biological process | central nervous system myelination |
| GO_0006531 | Biological process | aspartate metabolic process |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0016811 | Molecular function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| GO_0016788 | Molecular function | hydrolase activity, acting on ester bonds |
| GO_0019807 | Molecular function | aspartoacylase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ASPA |
| Protein name | Aspartoacylase Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2) Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) |
| Synonyms | hCG_32633 ACY2 ASP |
| Description | FUNCTION: Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids. . FUNCTION: Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids. . FUNCTION: Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids. . FUNCTION: Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids. . |
| Accessions | I3L0T3 ENST00000577034.1 Q6FH48 P45381 ENST00000263080.3 I3L4M0 ENST00000456349.6 ENST00000571278.1 |
