Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 9 studies | 29% ± 10% | |
non-classical monocyte | 9 studies | 31% ± 11% | |
ciliated cell | 8 studies | 24% ± 7% | |
conventional dendritic cell | 7 studies | 29% ± 16% | |
regulatory T cell | 6 studies | 17% ± 1% | |
macrophage | 6 studies | 18% ± 4% | |
monocyte | 5 studies | 17% ± 2% | |
epithelial cell | 5 studies | 35% ± 13% | |
dendritic cell | 5 studies | 35% ± 13% | |
type I pneumocyte | 5 studies | 24% ± 4% | |
CD8-positive, alpha-beta T cell | 4 studies | 17% ± 1% | |
club cell | 4 studies | 20% ± 5% | |
natural killer cell | 4 studies | 18% ± 1% | |
goblet cell | 4 studies | 21% ± 3% | |
plasmacytoid dendritic cell | 4 studies | 20% ± 4% | |
CD4-positive, alpha-beta memory T cell | 3 studies | 16% ± 1% | |
secretory cell | 3 studies | 25% ± 7% | |
squamous epithelial cell | 3 studies | 45% ± 19% | |
myeloid cell | 3 studies | 20% ± 2% | |
endothelial cell | 3 studies | 21% ± 6% | |
basal cell | 3 studies | 36% ± 14% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 7 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 1690.29 | 180 / 180 | 100% | 39.95 | 430 / 430 |
pancreas | 100% | 2881.29 | 328 / 328 | 100% | 56.94 | 178 / 178 |
esophagus | 100% | 3406.66 | 1444 / 1445 | 100% | 41.99 | 183 / 183 |
stomach | 100% | 4636.63 | 359 / 359 | 100% | 51.84 | 285 / 286 |
intestine | 100% | 3797.89 | 966 / 966 | 100% | 63.96 | 525 / 527 |
thymus | 100% | 4954.53 | 653 / 653 | 100% | 35.03 | 602 / 605 |
prostate | 100% | 6437.95 | 245 / 245 | 99% | 56.02 | 499 / 502 |
breast | 100% | 3918.92 | 459 / 459 | 99% | 44.69 | 1104 / 1118 |
adrenal gland | 100% | 3011.72 | 258 / 258 | 99% | 22.53 | 227 / 230 |
lung | 100% | 5065.21 | 578 / 578 | 99% | 35.63 | 1138 / 1155 |
bladder | 100% | 3217.24 | 21 / 21 | 98% | 51.32 | 496 / 504 |
uterus | 100% | 2166.41 | 170 / 170 | 98% | 45.93 | 451 / 459 |
brain | 97% | 1991.08 | 2571 / 2642 | 100% | 23.18 | 702 / 705 |
skin | 100% | 3217.55 | 1805 / 1809 | 96% | 17.43 | 455 / 472 |
kidney | 100% | 4091.33 | 89 / 89 | 94% | 21.93 | 848 / 901 |
liver | 100% | 2649.43 | 226 / 226 | 94% | 19.61 | 382 / 406 |
adipose | 100% | 2489.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 39.30 | 29 / 29 |
spleen | 100% | 7069.23 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 36.69 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 58.38 | 1 / 1 |
heart | 99% | 1887.45 | 856 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 4443.09 | 921 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 97% | 1581.54 | 1300 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 12.74 | 73 / 80 |
muscle | 90% | 1024.78 | 724 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0015031 | Biological process | protein transport |
GO_0016567 | Biological process | protein ubiquitination |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0006858 | Biological process | extracellular transport |
GO_0045746 | Biological process | negative regulation of Notch signaling pathway |
GO_0140112 | Biological process | extracellular vesicle biogenesis |
GO_0070062 | Cellular component | extracellular exosome |
GO_1903561 | Cellular component | extracellular vesicle |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0005737 | Cellular component | cytoplasm |
GO_1990756 | Molecular function | ubiquitin-like ligase-substrate adaptor activity |
GO_1990763 | Molecular function | arrestin family protein binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ARRDC1 |
Protein name | Arrestin domain containing 1 Arrestin domain-containing protein 1 (Alpha-arrestin 1) |
Synonyms | |
Description | FUNCTION: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates . Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles . More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles . By participating in the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway . . |
Accessions | ENST00000431925.6 Q5T370 Q5T371 Q8N5I2 ENST00000461627.1 F2Z3I4 ENST00000371421.9 ENST00000419386.1 |