ARHGEF16 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	23% ± 6%	Explore
goblet cell	3 studies	17% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ARHGEF16 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	1201.82	328 / 328	98%	39.14	175 / 178
thymus	100%	2200.02	652 / 653	93%	19.28	562 / 605
prostate	93%	2110.60	228 / 245	99%	23.56	496 / 502
kidney	100%	3211.17	89 / 89	89%	22.65	803 / 901
lung	88%	660.99	510 / 578	96%	24.23	1109 / 1155
breast	90%	993.30	411 / 459	93%	17.88	1040 / 1118
stomach	81%	2238.91	289 / 359	97%	32.14	276 / 286
intestine	66%	2423.27	641 / 966	98%	40.26	516 / 527
esophagus	55%	1135.47	801 / 1445	97%	28.09	178 / 183
bladder	57%	804.86	12 / 21	93%	27.39	467 / 504
liver	88%	681.58	199 / 226	55%	10.13	222 / 406
ovary	33%	168.36	60 / 180	78%	9.22	335 / 430
tonsil	0%	0	0 / 0	100%	39.95	45 / 45
ureter	0%	0	0 / 0	100%	28.28	1 / 1
uterus	9%	78.89	15 / 170	87%	32.05	401 / 459
skin	72%	740.52	1298 / 1809	24%	2.63	112 / 472
adipose	55%	309.20	667 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	21%	1.61	17 / 80
brain	17%	79.60	457 / 2642	2%	0.14	12 / 705
spleen	15%	57.98	35 / 241	0%	0	0 / 0
muscle	8%	46.59	68 / 803	0%	0	0 / 0
adrenal gland	2%	9.21	6 / 258	3%	0.71	7 / 230
blood vessel	4%	17.23	53 / 1335	0%	0	0 / 0
heart	3%	9.00	22 / 861	0%	0	0 / 0
peripheral blood	0%	1.79	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_1903078	Biological process	positive regulation of protein localization to plasma membrane
GO_0060326	Biological process	cell chemotaxis
GO_0090630	Biological process	activation of GTPase activity
GO_0005829	Cellular component	cytosol
GO_0045296	Molecular function	cadherin binding
GO_0030165	Molecular function	PDZ domain binding
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0005515	Molecular function	protein binding
GO_0030971	Molecular function	receptor tyrosine kinase binding
GO_0031267	Molecular function	small GTPase binding

Gene name	ARHGEF16
Protein name	Alternative protein ARHGEF16 Rho guanine nucleotide exchange factor 16 ARHGEF16 Rho guanine nucleotide exchange factor 16 (Ephexin-4)
Synonyms	EPHEXIN4 NBR
Description	FUNCTION: Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6. .
Accessions	A0A2X0SFX5 Q5VV41 B0QZD4 ENST00000418137.1 ENST00000378371.6 [Q5VV41-2] ENST00000378378.9 [Q5VV41-1] ENST00000445297.5 B0QZD3 ENST00000378373.5 [Q5VV41-2] L8EAP0

ARHGEF16 report