Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 15 studies | 36% ± 12% | |
oligodendrocyte | 15 studies | 56% ± 20% | |
glutamatergic neuron | 12 studies | 58% ± 21% | |
oligodendrocyte precursor cell | 12 studies | 45% ± 21% | |
GABAergic neuron | 11 studies | 48% ± 26% | |
type II pneumocyte | 10 studies | 35% ± 13% | |
club cell | 9 studies | 39% ± 17% | |
neuron | 7 studies | 40% ± 15% | |
endothelial cell | 7 studies | 28% ± 10% | |
respiratory goblet cell | 6 studies | 45% ± 18% | |
astrocyte | 6 studies | 34% ± 14% | |
retinal ganglion cell | 5 studies | 28% ± 9% | |
mucus secreting cell | 5 studies | 35% ± 13% | |
goblet cell | 5 studies | 51% ± 27% | |
interneuron | 5 studies | 59% ± 27% | |
epithelial cell | 4 studies | 25% ± 10% | |
secretory cell | 4 studies | 30% ± 10% | |
enteroendocrine cell | 4 studies | 51% ± 16% | |
ionocyte | 3 studies | 24% ± 6% | |
pancreatic A cell | 3 studies | 53% ± 19% | |
granule cell | 3 studies | 69% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 95% | 4628.70 | 232 / 245 | 100% | 89.47 | 501 / 502 |
pancreas | 100% | 3111.86 | 328 / 328 | 81% | 14.17 | 145 / 178 |
brain | 100% | 6609.08 | 2641 / 2642 | 81% | 19.24 | 570 / 705 |
breast | 79% | 1788.92 | 362 / 459 | 93% | 39.57 | 1040 / 1118 |
lung | 95% | 2286.67 | 548 / 578 | 74% | 11.81 | 853 / 1155 |
stomach | 76% | 3715.24 | 273 / 359 | 90% | 16.07 | 257 / 286 |
intestine | 57% | 826.53 | 546 / 966 | 89% | 14.81 | 471 / 527 |
bladder | 33% | 1103.67 | 7 / 21 | 70% | 9.57 | 352 / 504 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.73 | 1 / 1 |
adrenal gland | 18% | 345.99 | 47 / 258 | 67% | 34.16 | 155 / 230 |
kidney | 30% | 339.38 | 27 / 89 | 44% | 5.23 | 398 / 901 |
esophagus | 7% | 67.11 | 104 / 1445 | 62% | 16.34 | 113 / 183 |
thymus | 48% | 375.64 | 313 / 653 | 16% | 1.58 | 96 / 605 |
skin | 46% | 518.28 | 834 / 1809 | 16% | 1.61 | 77 / 472 |
adipose | 59% | 585.51 | 707 / 1204 | 0% | 0 | 0 / 0 |
uterus | 22% | 197.35 | 37 / 170 | 34% | 5.09 | 158 / 459 |
tonsil | 0% | 0 | 0 / 0 | 24% | 2.08 | 11 / 45 |
ovary | 1% | 8.09 | 2 / 180 | 19% | 1.49 | 82 / 430 |
liver | 2% | 14.77 | 4 / 226 | 15% | 1.52 | 61 / 406 |
heart | 15% | 124.14 | 129 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 6% | 0.55 | 5 / 80 |
blood vessel | 3% | 22.96 | 38 / 1335 | 0% | 0 | 0 / 0 |
spleen | 2% | 13.33 | 5 / 241 | 0% | 0 | 0 / 0 |
muscle | 1% | 8.15 | 5 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 1.05 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032012 | Biological process | regulation of ARF protein signal transduction |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0030658 | Cellular component | transport vesicle membrane |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
Gene name | ARFGEF3 |
Protein name | Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3) KIAA1244 |
Synonyms | BIG3 KIAA1244 C6orf92 |
Description | FUNCTION: Participates in the regulation of systemic glucose homeostasis, where it negatively regulates insulin granule biogenesis in pancreatic islet beta cells (By similarity). Also regulates glucagon granule production in pancreatic alpha cells (By similarity). Inhibits nuclear translocation of the transcriptional coregulator PHB2 and may enhance estrogen receptor alpha (ESR1) transcriptional activity in breast cancer cells . . |
Accessions | Q5TH69 ENST00000251691.5 B5MDV5 |