ANKRD2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ANKRD2 at tissue level.

III. Associated gene sets

GO_0045662Biological processnegative regulation of myoblast differentiation
GO_0006936Biological processmuscle contraction
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0007517Biological processmuscle organ development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0016605Cellular componentPML body
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000791Cellular componenteuchromatin
GO_0031674Cellular componentI band
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0061629Molecular functionRNA polymerase II-specific DNA-binding transcription factor binding
GO_0043422Molecular functionprotein kinase B binding
GO_0005515Molecular functionprotein binding
GO_0008307Molecular functionstructural constituent of muscle

IV. Literature review

[source]
Gene nameANKRD2
Protein nameAnkyrin repeat domain 2
Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp)
SynonymsARPP
DescriptionFUNCTION: Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress. .

AccessionsENST00000298808.9 [Q9GZV1-2]
Q5T457
ENST00000455090.1
ENST00000370655.6
Q9GZV1
A0A0A0MRN9
ENST00000307518.9 [Q9GZV1-1]