Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal ganglion cell | 7 studies | 53% ± 19% | |
| GABAergic neuron | 7 studies | 54% ± 24% | |
| erythrocyte | 7 studies | 51% ± 22% | |
| glutamatergic neuron | 5 studies | 33% ± 22% | |
| retinal cone cell | 5 studies | 23% ± 5% | |
| interneuron | 4 studies | 51% ± 22% | |
| GABAergic interneuron | 3 studies | 38% ± 7% | |
| endothelial cell | 3 studies | 39% ± 17% | |
| erythroblast | 3 studies | 45% ± 19% | |
| cardiac muscle cell | 3 studies | 19% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 30% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 76% | 4230.94 | 1997 / 2642 | 84% | 4.77 | 589 / 705 |
| muscle | 100% | 14105.01 | 803 / 803 | 0% | 0 | 0 / 0 |
| adrenal gland | 34% | 279.39 | 87 / 258 | 65% | 4.34 | 150 / 230 |
| heart | 97% | 3740.69 | 838 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 2136.01 | 847 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 3.46 | 21 / 29 |
| pancreas | 1% | 4.15 | 2 / 328 | 70% | 2.49 | 125 / 178 |
| kidney | 7% | 38.35 | 6 / 89 | 62% | 3.66 | 555 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 62% | 1.77 | 28 / 45 |
| blood vessel | 58% | 492.82 | 778 / 1335 | 0% | 0 | 0 / 0 |
| esophagus | 4% | 25.48 | 62 / 1445 | 50% | 2.41 | 92 / 183 |
| prostate | 7% | 101.02 | 18 / 245 | 38% | 1.10 | 190 / 502 |
| uterus | 0% | 0 | 0 / 170 | 45% | 2.18 | 205 / 459 |
| spleen | 40% | 414.69 | 97 / 241 | 0% | 0 | 0 / 0 |
| stomach | 6% | 38.96 | 23 / 359 | 30% | 1.38 | 87 / 286 |
| lung | 9% | 59.44 | 50 / 578 | 25% | 1.25 | 284 / 1155 |
| intestine | 2% | 8.88 | 18 / 966 | 21% | 0.90 | 109 / 527 |
| bladder | 0% | 0 | 0 / 21 | 22% | 0.91 | 111 / 504 |
| breast | 3% | 20.14 | 13 / 459 | 17% | 2.32 | 194 / 1118 |
| ovary | 1% | 2.43 | 1 / 180 | 17% | 0.56 | 74 / 430 |
| skin | 0% | 10.16 | 9 / 1809 | 11% | 0.48 | 51 / 472 |
| thymus | 3% | 25.33 | 18 / 653 | 5% | 0.15 | 32 / 605 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.24 | 6 / 80 |
| adipose | 7% | 37.05 | 88 / 1204 | 0% | 0 | 0 / 0 |
| liver | 1% | 8.24 | 2 / 226 | 6% | 0.22 | 23 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0045199 | Biological process | maintenance of epithelial cell apical/basal polarity |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0007165 | Biological process | signal transduction |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0006887 | Biological process | exocytosis |
| GO_0010638 | Biological process | positive regulation of organelle organization |
| GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030018 | Cellular component | Z disc |
| GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0043005 | Cellular component | neuron projection |
| GO_0014731 | Cellular component | spectrin-associated cytoskeleton |
| GO_0030673 | Cellular component | axolemma |
| GO_0005829 | Cellular component | cytosol |
| GO_0170014 | Cellular component | ankyrin-1 complex |
| GO_0016529 | Cellular component | sarcoplasmic reticulum |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0031430 | Cellular component | M band |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0030507 | Molecular function | spectrin binding |
| GO_0019903 | Molecular function | protein phosphatase binding |
| GO_0005200 | Molecular function | structural constituent of cytoskeleton |
| GO_0005198 | Molecular function | structural molecule activity |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0051117 | Molecular function | ATPase binding |
| GO_0008093 | Molecular function | cytoskeletal anchor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ANK1 |
| Protein name | Ankyrin 1 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) ANK1 protein (Ankyrin 1) |
| Synonyms | ANK |
| Description | FUNCTION: Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane . Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions. .; FUNCTION: [Isoform Mu17]: Together with obscurin in skeletal muscle may provide a molecular link between the sarcoplasmic reticulum and myofibrils. . |
| Accessions | ENST00000518061.1 ENST00000705521.1 P16157 ENST00000314214.12 [P16157-17] ENST00000705522.1 Q6PK32 ENST00000289734.13 [P16157-3] A0A994J7F8 ENST00000645531.1 ENST00000522231.5 C9JN86 ENST00000348036.8 [P16157-22] A0A2R8Y4B0 A0A994J4W8 ENST00000335651.6 H0YBS0 ENST00000522543.6 [P16157-23] ENST00000265709.14 [P16157-21] ENST00000520299.5 H0YAY8 ENST00000347528.8 [P16157-1] |
