ANGPTL7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ANGPTL7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ANGPTL7 at tissue level.

III. Associated gene sets

GO_1901346Biological processnegative regulation of vasculature development involved in avascular cornea development in camera-type eye
GO_0006979Biological processresponse to oxidative stress
GO_1903053Biological processregulation of extracellular matrix organization
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameANGPTL7
Protein nameAngiopoietin-related protein 7 (Angiopoietin-like factor) (Angiopoietin-like protein 7) (Cornea-derived transcript 6 protein)
SynonymsUNQ313/PRO356
CDT6
DescriptionFUNCTION: Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure . Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency . .

AccessionsENST00000376819.4
O43827