I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| rod bipolar cell | 3 studies | 50% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| rod bipolar cell | 3 studies | 50% ± 13% |
Insufficient scRNA-seq data for expression of AMIGO2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 3062.24 | 21 / 21 | 91% | 76.56 | 457 / 504 |
| breast | 100% | 3339.64 | 459 / 459 | 86% | 50.46 | 967 / 1118 |
| lung | 99% | 2161.03 | 575 / 578 | 83% | 40.34 | 962 / 1155 |
| adrenal gland | 100% | 2603.64 | 258 / 258 | 77% | 32.55 | 178 / 230 |
| intestine | 92% | 3421.87 | 893 / 966 | 74% | 19.58 | 391 / 527 |
| uterus | 99% | 3381.21 | 168 / 170 | 64% | 27.49 | 296 / 459 |
| thymus | 79% | 594.13 | 514 / 653 | 76% | 28.06 | 460 / 605 |
| kidney | 96% | 941.46 | 85 / 89 | 51% | 10.19 | 464 / 901 |
| ovary | 100% | 3838.44 | 180 / 180 | 47% | 7.96 | 201 / 430 |
| prostate | 94% | 1656.65 | 231 / 245 | 52% | 8.04 | 261 / 502 |
| esophagus | 60% | 417.97 | 871 / 1445 | 72% | 21.07 | 132 / 183 |
| pancreas | 27% | 134.53 | 89 / 328 | 96% | 56.16 | 171 / 178 |
| stomach | 51% | 570.13 | 184 / 359 | 71% | 15.48 | 203 / 286 |
| blood vessel | 100% | 7084.51 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2010.05 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 30.91 | 1 / 1 |
| adipose | 99% | 1476.16 | 1190 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 13.75 | 24 / 29 |
| skin | 57% | 500.50 | 1033 / 1809 | 24% | 4.47 | 111 / 472 |
| brain | 44% | 376.97 | 1170 / 2642 | 25% | 4.66 | 179 / 705 |
| heart | 38% | 273.69 | 331 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 33% | 7.70 | 15 / 45 |
| liver | 8% | 55.00 | 19 / 226 | 18% | 3.06 | 75 / 406 |
| peripheral blood | 7% | 37.56 | 62 / 929 | 0% | 0 | 0 / 0 |
| muscle | 2% | 14.15 | 18 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.20 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007420 | Biological process | brain development |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_0007157 | Biological process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0043069 | Biological process | negative regulation of programmed cell death |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | AMIGO2 |
| Protein name | Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA) |
| Synonyms | ALI1 |
| Description | FUNCTION: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| Accessions | Q86SJ2 ENST00000429635.1 ENST00000266581.4 ENST00000550413.2 |
