ALS2CL report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ALS2CL at tissue level.

III. Associated gene sets

GO_0016197Biological processendosomal transport
GO_0043087Biological processregulation of GTPase activity
GO_0005829Cellular componentcytosol
GO_0031410Cellular componentcytoplasmic vesicle
GO_0005737Cellular componentcytoplasm
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameALS2CL
Protein nameALS2 C-terminal-like protein
ALS2 C-terminal like
SynonymshCG_2043002
DescriptionFUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. .

AccessionsENST00000318962.9 [Q60I27-1]
H7C0M4
ENST00000434140.5
G5E9N5
Q60I27
ENST00000415953.5 [Q60I27-1]
ENST00000423707.5