Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 7 studies | 27% ± 9% | |
squamous epithelial cell | 3 studies | 43% ± 19% | |
podocyte | 3 studies | 75% ± 9% |
Insufficient scRNA-seq data for expression of ALS2CL at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 15735.68 | 651 / 653 | 96% | 30.23 | 583 / 605 |
pancreas | 91% | 2957.19 | 297 / 328 | 94% | 35.19 | 168 / 178 |
lung | 100% | 8614.21 | 576 / 578 | 82% | 13.33 | 943 / 1155 |
bladder | 86% | 3936.29 | 18 / 21 | 92% | 26.09 | 463 / 504 |
liver | 94% | 4026.52 | 212 / 226 | 75% | 10.97 | 305 / 406 |
esophagus | 77% | 10921.07 | 1118 / 1445 | 91% | 17.90 | 166 / 183 |
uterus | 78% | 3189.83 | 132 / 170 | 84% | 29.90 | 384 / 459 |
intestine | 71% | 3206.14 | 682 / 966 | 91% | 15.29 | 478 / 527 |
kidney | 100% | 22253.43 | 89 / 89 | 54% | 7.83 | 486 / 901 |
stomach | 59% | 1831.50 | 213 / 359 | 80% | 12.00 | 229 / 286 |
breast | 92% | 3802.03 | 424 / 459 | 42% | 3.24 | 472 / 1118 |
prostate | 89% | 4653.80 | 218 / 245 | 26% | 1.90 | 130 / 502 |
ovary | 37% | 916.28 | 66 / 180 | 68% | 10.29 | 292 / 430 |
spleen | 100% | 8259.66 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 56.33 | 1 / 1 |
heart | 96% | 4193.33 | 825 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 53% | 1326.62 | 136 / 258 | 38% | 2.87 | 88 / 230 |
blood vessel | 89% | 2960.98 | 1183 / 1335 | 0% | 0 | 0 / 0 |
skin | 72% | 13435.86 | 1305 / 1809 | 15% | 1.26 | 72 / 472 |
tonsil | 0% | 0 | 0 / 0 | 84% | 14.31 | 38 / 45 |
adipose | 84% | 2930.62 | 1014 / 1204 | 0% | 0 | 0 / 0 |
muscle | 42% | 946.06 | 338 / 803 | 0% | 0 | 0 / 0 |
brain | 34% | 1142.69 | 888 / 2642 | 7% | 0.43 | 47 / 705 |
lymph node | 0% | 0 | 0 / 0 | 28% | 2.05 | 8 / 29 |
eye | 0% | 0 | 0 / 0 | 3% | 0.14 | 2 / 80 |
peripheral blood | 1% | 15.53 | 7 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016197 | Biological process | endosomal transport |
GO_0043087 | Biological process | regulation of GTPase activity |
GO_0005829 | Cellular component | cytosol |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0005096 | Molecular function | GTPase activator activity |
Gene name | ALS2CL |
Protein name | ALS2 C-terminal-like protein ALS2 C-terminal like |
Synonyms | hCG_2043002 |
Description | FUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. . |
Accessions | ENST00000318962.9 [Q60I27-1] H7C0M4 ENST00000434140.5 G5E9N5 Q60I27 ENST00000415953.5 [Q60I27-1] ENST00000423707.5 |