Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 16 studies | 37% ± 16% | |
basal cell | 13 studies | 31% ± 16% | |
fibroblast | 10 studies | 26% ± 15% | |
endothelial cell | 8 studies | 29% ± 19% | |
epithelial cell | 8 studies | 35% ± 12% | |
oligodendrocyte precursor cell | 7 studies | 25% ± 9% | |
epithelial cell of proximal tubule | 6 studies | 24% ± 3% | |
connective tissue cell | 5 studies | 22% ± 9% | |
Mueller cell | 5 studies | 27% ± 7% | |
GABAergic neuron | 5 studies | 30% ± 11% | |
abnormal cell | 4 studies | 30% ± 8% | |
adipocyte | 4 studies | 19% ± 3% | |
glutamatergic neuron | 4 studies | 33% ± 10% | |
interneuron | 4 studies | 30% ± 18% | |
neuron | 4 studies | 28% ± 6% | |
oligodendrocyte | 4 studies | 24% ± 2% | |
progenitor cell | 3 studies | 18% ± 3% | |
ciliated cell | 3 studies | 23% ± 6% | |
neural progenitor cell | 3 studies | 21% ± 3% | |
ependymal cell | 3 studies | 37% ± 16% | |
intestinal crypt stem cell | 3 studies | 23% ± 5% | |
myofibroblast cell | 3 studies | 21% ± 5% | |
transit amplifying cell | 3 studies | 48% ± 29% | |
goblet cell | 3 studies | 16% ± 0% | |
hepatocyte | 3 studies | 32% ± 10% | |
myoepithelial cell | 3 studies | 40% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 7381.13 | 180 / 180 | 100% | 13.62 | 430 / 430 |
prostate | 100% | 3967.79 | 245 / 245 | 100% | 25.27 | 500 / 502 |
breast | 100% | 3431.94 | 458 / 459 | 99% | 17.17 | 1112 / 1118 |
kidney | 100% | 4836.49 | 89 / 89 | 99% | 15.70 | 890 / 901 |
thymus | 100% | 3404.45 | 652 / 653 | 99% | 14.32 | 597 / 605 |
liver | 100% | 4936.49 | 225 / 226 | 98% | 23.70 | 399 / 406 |
brain | 100% | 7332.53 | 2642 / 2642 | 97% | 25.96 | 685 / 705 |
skin | 100% | 3822.64 | 1808 / 1809 | 95% | 12.88 | 450 / 472 |
intestine | 99% | 2239.63 | 959 / 966 | 96% | 10.23 | 505 / 527 |
adrenal gland | 100% | 5382.11 | 258 / 258 | 95% | 9.33 | 218 / 230 |
stomach | 99% | 2391.24 | 357 / 359 | 92% | 8.42 | 263 / 286 |
pancreas | 98% | 1607.54 | 321 / 328 | 93% | 8.24 | 165 / 178 |
uterus | 100% | 3379.47 | 170 / 170 | 85% | 13.77 | 391 / 459 |
esophagus | 99% | 3045.33 | 1429 / 1445 | 86% | 7.68 | 157 / 183 |
lung | 96% | 2008.09 | 555 / 578 | 80% | 7.83 | 929 / 1155 |
bladder | 100% | 2571.48 | 21 / 21 | 70% | 9.09 | 351 / 504 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.22 | 1 / 1 |
adipose | 100% | 2344.18 | 1199 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 2599.96 | 1328 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 9.10 | 75 / 80 |
heart | 89% | 1812.37 | 769 / 861 | 0% | 0 | 0 / 0 |
spleen | 72% | 744.81 | 173 / 241 | 0% | 0 | 0 / 0 |
muscle | 60% | 669.99 | 481 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 58% | 8.93 | 26 / 45 |
lymph node | 0% | 0 | 0 / 0 | 14% | 0.86 | 4 / 29 |
peripheral blood | 7% | 90.81 | 61 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0019285 | Biological process | glycine betaine biosynthetic process from choline |
GO_0007605 | Biological process | sensory perception of sound |
GO_0042426 | Biological process | choline catabolic process |
GO_0006081 | Biological process | cellular aldehyde metabolic process |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0005634 | Cellular component | nucleus |
GO_0004029 | Molecular function | aldehyde dehydrogenase (NAD+) activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0043878 | Molecular function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
GO_0008802 | Molecular function | betaine-aldehyde dehydrogenase (NAD+) activity |
GO_0004043 | Molecular function | L-aminoadipate-semialdehyde dehydrogenase activity |
Gene name | ALDH7A1 |
Protein name | aldehyde dehydrogenase (NAD(+)) (EC 1.2.1.3) Aldehyde dehydrogenase 7 family member A1 Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase) |
Synonyms | ATQ1 |
Description | FUNCTION: Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. . |
Accessions | A0A1B0GW65 A0A1B0GTG2 ENST00000510111.6 ENST00000637206.1 A0A1B0GUY0 A0A0J9YWM6 ENST00000509459.6 A0A1B0GV49 A0A1B0GVU0 A0A0J9YWK1 ENST00000636879.1 ENST00000503281.6 ENST00000637964.1 A0A1B0GW82 A0A0J9YWF7 F8VVF2 ENST00000635851.1 ENST00000636225.1 ENST00000636743.1 ENST00000638008.1 F8WDY6 ENST00000636872.1 ENST00000636886.1 P49419 ENST00000409134.8 [P49419-1] A0A1B0GTJ4 ENST00000637782.1 ENST00000636808.1 A0A1B0GUA1 A0A1B0GTY9 ENST00000458249.6 A0A1B0GW77 ENST00000553117.5 [P49419-4] ENST00000637272.1 ENST00000413020.6 H0YHM6 F8WD33 ENST00000412186.2 ENST00000509270.2 ENST00000637292.1 |