I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 11 studies | 36% ± 12% | |
| glutamatergic neuron | 3 studies | 19% ± 1% | |
| astrocyte | 3 studies | 25% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 11 studies | 36% ± 12% | |
| glutamatergic neuron | 3 studies | 19% ± 1% | |
| astrocyte | 3 studies | 25% ± 10% |
Insufficient scRNA-seq data for expression of AK8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 353.03 | 653 / 653 | 100% | 7.57 | 604 / 605 |
| brain | 99% | 143.74 | 2606 / 2642 | 99% | 6.34 | 697 / 705 |
| prostate | 99% | 85.22 | 243 / 245 | 97% | 2.88 | 489 / 502 |
| ovary | 98% | 102.23 | 177 / 180 | 93% | 4.13 | 402 / 430 |
| kidney | 99% | 140.76 | 88 / 89 | 91% | 5.62 | 824 / 901 |
| breast | 97% | 94.88 | 445 / 459 | 92% | 6.42 | 1025 / 1118 |
| adrenal gland | 97% | 95.53 | 251 / 258 | 84% | 2.48 | 193 / 230 |
| lung | 94% | 159.70 | 545 / 578 | 77% | 2.85 | 885 / 1155 |
| uterus | 98% | 105.36 | 167 / 170 | 61% | 2.49 | 279 / 459 |
| esophagus | 91% | 55.56 | 1314 / 1445 | 58% | 1.87 | 106 / 183 |
| pancreas | 63% | 27.39 | 206 / 328 | 83% | 2.71 | 148 / 178 |
| bladder | 86% | 49.62 | 18 / 21 | 44% | 1.11 | 224 / 504 |
| skin | 89% | 139.58 | 1611 / 1809 | 38% | 0.88 | 180 / 472 |
| stomach | 68% | 48.88 | 243 / 359 | 50% | 1.79 | 143 / 286 |
| intestine | 71% | 47.69 | 690 / 966 | 38% | 0.97 | 199 / 527 |
| eye | 0% | 0 | 0 / 0 | 96% | 2.53 | 77 / 80 |
| adipose | 92% | 73.56 | 1102 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 84% | 51.63 | 1123 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 6.20 | 37 / 45 |
| spleen | 65% | 28.39 | 157 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 2.13 | 18 / 29 |
| heart | 33% | 13.36 | 282 / 861 | 0% | 0 | 0 / 0 |
| liver | 1% | 0.43 | 3 / 226 | 22% | 0.75 | 89 / 406 |
| peripheral blood | 10% | 4.79 | 93 / 929 | 0% | 0 | 0 / 0 |
| muscle | 3% | 1.07 | 22 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0046940 | Biological process | nucleoside monophosphate phosphorylation |
| GO_0021591 | Biological process | ventricular system development |
| GO_0005930 | Cellular component | axoneme |
| GO_0005829 | Cellular component | cytosol |
| GO_0036126 | Cellular component | sperm flagellum |
| GO_0097729 | Cellular component | 9+2 motile cilium |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004127 | Molecular function | (d)CMP kinase activity |
| GO_0004017 | Molecular function | adenylate kinase activity |
| GO_0004550 | Molecular function | nucleoside diphosphate kinase activity |
| GO_0016208 | Molecular function | AMP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | AK8 |
| Protein name | Adenylate kinase 8 (AK 8) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 8) |
| Synonyms | C9orf98 |
| Description | FUNCTION: Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. . |
| Accessions | ENST00000298545.4 [Q96MA6-1] Q96MA6 |
