Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 4 studies | 33% ± 11% | |
hematopoietic precursor cell | 3 studies | 17% ± 1% | |
ciliated cell | 3 studies | 23% ± 2% | |
erythroblast | 3 studies | 25% ± 6% | |
glutamatergic neuron | 3 studies | 22% ± 4% | |
dendritic cell | 3 studies | 31% ± 4% |
Insufficient scRNA-seq data for expression of AIMP2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 100% | 784.58 | 1809 / 1809 | 100% | 36.49 | 472 / 472 |
esophagus | 99% | 514.69 | 1436 / 1445 | 100% | 28.57 | 183 / 183 |
breast | 100% | 546.44 | 459 / 459 | 99% | 26.48 | 1111 / 1118 |
intestine | 100% | 613.57 | 963 / 966 | 99% | 41.71 | 524 / 527 |
bladder | 100% | 496.33 | 21 / 21 | 99% | 31.82 | 498 / 504 |
stomach | 98% | 379.30 | 353 / 359 | 100% | 39.67 | 286 / 286 |
thymus | 100% | 567.39 | 651 / 653 | 98% | 22.02 | 595 / 605 |
kidney | 100% | 565.85 | 89 / 89 | 97% | 19.54 | 877 / 901 |
liver | 99% | 471.31 | 224 / 226 | 97% | 24.98 | 395 / 406 |
prostate | 97% | 346.05 | 237 / 245 | 99% | 26.93 | 497 / 502 |
brain | 96% | 296.83 | 2527 / 2642 | 100% | 31.41 | 705 / 705 |
uterus | 96% | 398.16 | 163 / 170 | 99% | 28.15 | 453 / 459 |
pancreas | 93% | 256.84 | 305 / 328 | 99% | 20.18 | 176 / 178 |
lung | 92% | 423.28 | 530 / 578 | 100% | 29.75 | 1152 / 1155 |
adrenal gland | 100% | 638.70 | 257 / 258 | 92% | 17.06 | 211 / 230 |
ovary | 87% | 238.91 | 157 / 180 | 100% | 38.84 | 429 / 430 |
adipose | 100% | 557.57 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 36.97 | 29 / 29 |
muscle | 100% | 2382.37 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 394.75 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 27.41 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.54 | 1 / 1 |
blood vessel | 99% | 416.76 | 1319 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 33.86 | 79 / 80 |
heart | 94% | 637.51 | 806 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 73% | 370.54 | 682 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006412 | Biological process | translation |
GO_0006915 | Biological process | apoptotic process |
GO_0016567 | Biological process | protein ubiquitination |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0031398 | Biological process | positive regulation of protein ubiquitination |
GO_0060510 | Biological process | type II pneumocyte differentiation |
GO_0065003 | Biological process | protein-containing complex assembly |
GO_0017101 | Cellular component | aminoacyl-tRNA synthetase multienzyme complex |
GO_0005829 | Cellular component | cytosol |
GO_0016020 | Cellular component | membrane |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0060090 | Molecular function | molecular adaptor activity |
Gene name | AIMP2 |
Protein name | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1) Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 |
Synonyms | PRO0992 JTV1 |
Description | FUNCTION: Required for assembly and stability of the aminoacyl-tRNA synthase complex . Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. . |
Accessions | F8WCL2 A8MU58 ENST00000415999.1 ENST00000223029.8 [Q13155-1] ENST00000395236.2 [Q13155-2] Q13155 ENST00000400479.6 |