Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 10 studies | 28% ± 12% | |
| endothelial cell | 8 studies | 25% ± 10% | |
| microglial cell | 8 studies | 25% ± 8% | |
| mast cell | 8 studies | 24% ± 6% | |
| macrophage | 8 studies | 29% ± 8% | |
| GABAergic neuron | 7 studies | 37% ± 20% | |
| epithelial cell | 6 studies | 28% ± 9% | |
| neuron | 5 studies | 35% ± 15% | |
| myeloid cell | 5 studies | 22% ± 8% | |
| dendritic cell | 5 studies | 21% ± 5% | |
| fibroblast | 5 studies | 18% ± 2% | |
| astrocyte | 5 studies | 35% ± 14% | |
| oligodendrocyte precursor cell | 5 studies | 31% ± 9% | |
| goblet cell | 5 studies | 27% ± 11% | |
| interneuron | 5 studies | 40% ± 24% | |
| adipocyte | 4 studies | 19% ± 3% | |
| glutamatergic neuron | 4 studies | 56% ± 17% | |
| hematopoietic precursor cell | 3 studies | 25% ± 6% | |
| GABAergic interneuron | 3 studies | 21% ± 4% | |
| ciliated cell | 3 studies | 23% ± 3% | |
| alveolar macrophage | 3 studies | 36% ± 12% | |
| monocyte | 3 studies | 26% ± 5% | |
| transit amplifying cell | 3 studies | 28% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2307.73 | 1445 / 1445 | 100% | 29.26 | 183 / 183 |
| intestine | 100% | 2770.15 | 966 / 966 | 100% | 25.24 | 526 / 527 |
| lung | 100% | 2024.23 | 578 / 578 | 100% | 24.24 | 1152 / 1155 |
| brain | 100% | 1667.77 | 2635 / 2642 | 100% | 20.11 | 705 / 705 |
| uterus | 100% | 2413.94 | 170 / 170 | 100% | 23.80 | 457 / 459 |
| pancreas | 100% | 1633.73 | 327 / 328 | 99% | 20.09 | 177 / 178 |
| thymus | 100% | 1633.00 | 653 / 653 | 99% | 14.30 | 599 / 605 |
| stomach | 100% | 1353.91 | 359 / 359 | 99% | 24.55 | 283 / 286 |
| bladder | 100% | 2473.43 | 21 / 21 | 99% | 20.05 | 498 / 504 |
| ovary | 100% | 1584.14 | 180 / 180 | 99% | 12.23 | 424 / 430 |
| kidney | 100% | 1786.31 | 89 / 89 | 98% | 28.93 | 885 / 901 |
| liver | 100% | 1707.65 | 226 / 226 | 98% | 15.10 | 396 / 406 |
| breast | 100% | 2292.32 | 459 / 459 | 97% | 24.49 | 1086 / 1118 |
| skin | 100% | 2161.84 | 1805 / 1809 | 97% | 27.24 | 458 / 472 |
| adrenal gland | 100% | 2374.91 | 258 / 258 | 89% | 9.67 | 205 / 230 |
| prostate | 99% | 1344.96 | 242 / 245 | 77% | 6.48 | 388 / 502 |
| blood vessel | 100% | 2357.18 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.83 | 29 / 29 |
| muscle | 100% | 1902.63 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1654.97 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 21.13 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.45 | 1 / 1 |
| adipose | 100% | 2701.14 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| heart | 98% | 1339.91 | 841 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 88% | 10.42 | 70 / 80 |
| peripheral blood | 82% | 1473.30 | 765 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008611 | Biological process | ether lipid biosynthetic process |
| GO_0008610 | Biological process | lipid biosynthetic process |
| GO_0005778 | Cellular component | peroxisomal membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005777 | Cellular component | peroxisome |
| GO_0005782 | Cellular component | peroxisomal matrix |
| GO_0016020 | Cellular component | membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0071949 | Molecular function | FAD binding |
| GO_0008609 | Molecular function | alkylglycerone-phosphate synthase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | AGPS |
| Protein name | Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase) Alkylglycerone-phosphate synthase (Alkyl-DHAP synthase) (EC 2.5.1.26) |
| Synonyms | AAG5 |
| Description | FUNCTION: Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . FUNCTION: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. . |
| Accessions | ENST00000681028.1 ENST00000680770.1 A0A7P0T984 A0A7P0T8Q7 A0A2R8YEL0 Q53S12 ENST00000642466.2 A0A1B0GWA2 ENST00000637633.2 A0A7P0TAL3 A0A7P0TA54 A0A7P0T9C9 ENST00000681032.1 ENST00000679478.1 ENST00000409888.1 ENST00000264167.11 A0A7P0T857 O00116 B8ZZ81 A0A7P0TAU9 ENST00000679459.1 ENST00000680155.1 Q53SN7 ENST00000679994.1 ENST00000681565.1 B7Z3Q4 ENST00000680893.1 Q53SG6 ENST00000681449.1 ENST00000681752.1 |