Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 13 studies | 40% ± 19% | |
| endothelial cell | 9 studies | 27% ± 10% | |
| pericyte | 6 studies | 27% ± 8% | |
| brush cell | 4 studies | 42% ± 20% |
Insufficient scRNA-seq data for expression of AFAP1L2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 16813.03 | 653 / 653 | 98% | 131.69 | 593 / 605 |
| brain | 98% | 2456.07 | 2596 / 2642 | 92% | 31.41 | 650 / 705 |
| esophagus | 99% | 2272.04 | 1437 / 1445 | 88% | 25.83 | 161 / 183 |
| pancreas | 92% | 1703.15 | 301 / 328 | 95% | 25.36 | 169 / 178 |
| uterus | 100% | 5212.33 | 170 / 170 | 84% | 26.41 | 387 / 459 |
| breast | 97% | 2564.50 | 443 / 459 | 81% | 17.82 | 909 / 1118 |
| intestine | 97% | 2326.98 | 939 / 966 | 80% | 13.45 | 420 / 527 |
| ovary | 100% | 2950.54 | 180 / 180 | 74% | 24.40 | 318 / 430 |
| prostate | 100% | 2862.33 | 244 / 245 | 73% | 10.01 | 366 / 502 |
| bladder | 95% | 1398.71 | 20 / 21 | 69% | 14.46 | 349 / 504 |
| kidney | 99% | 2751.48 | 88 / 89 | 57% | 10.30 | 518 / 901 |
| lung | 84% | 1231.31 | 487 / 578 | 69% | 14.68 | 798 / 1155 |
| skin | 71% | 1284.53 | 1284 / 1809 | 71% | 32.83 | 334 / 472 |
| stomach | 69% | 1240.58 | 246 / 359 | 67% | 9.14 | 191 / 286 |
| spleen | 100% | 13947.02 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 23.94 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 26.07 | 39 / 45 |
| adipose | 87% | 1564.46 | 1042 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 77% | 1028.41 | 1027 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 6.96 | 18 / 29 |
| heart | 41% | 422.11 | 351 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 14% | 126.53 | 35 / 258 | 27% | 3.00 | 61 / 230 |
| liver | 1% | 6.89 | 2 / 226 | 6% | 0.87 | 24 / 406 |
| peripheral blood | 5% | 78.45 | 47 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 5% | 0.35 | 4 / 80 |
| muscle | 4% | 35.79 | 34 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
| GO_0032675 | Biological process | regulation of interleukin-6 production |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0006954 | Biological process | inflammatory response |
| GO_0007346 | Biological process | regulation of mitotic cell cycle |
| GO_0032757 | Biological process | positive regulation of interleukin-8 production |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030296 | Molecular function | protein tyrosine kinase activator activity |
| GO_0042169 | Molecular function | SH2 domain binding |
| GO_0017124 | Molecular function | SH3 domain binding |
| Gene name | AFAP1L2 |
| Protein name | Actin filament-associated protein 1-like 2 (AFAP1-like protein 2) Actin filament associated protein 1 like 2 |
| Synonyms | KIAA1914 XB130 |
| Description | FUNCTION: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. . |
| Accessions | ENST00000696688.1 Q8N4X5 ENST00000369271.7 [Q8N4X5-2] F6QUH3 ENST00000304129.9 [Q8N4X5-1] ENST00000419268.1 A0A8Q3SIY9 |