ADTRP | OmnibusX

Name	Number of supported studies	Average coverage
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	23% ± 6%	Explore
regulatory T cell	6 studies	21% ± 5%	Explore
renal alpha-intercalated cell	4 studies	29% ± 8%	Explore
enterocyte	3 studies	22% ± 3%	Explore
retinal pigment epithelial cell	3 studies	30% ± 3%	Explore
epithelial cell	3 studies	21% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADTRP at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	96%	490.43	553 / 578	75%	4.87	869 / 1155
stomach	77%	1118.87	275 / 359	77%	8.53	219 / 286
kidney	96%	526.26	85 / 89	42%	2.73	380 / 901
intestine	57%	1794.87	546 / 966	81%	9.96	426 / 527
bladder	48%	143.57	10 / 21	66%	5.39	334 / 504
skin	84%	897.43	1515 / 1809	29%	0.96	136 / 472
lymph node	0%	0	0 / 0	93%	9.43	27 / 29
tonsil	0%	0	0 / 0	89%	7.63	40 / 45
esophagus	9%	13.63	123 / 1445	80%	7.65	146 / 183
pancreas	1%	1.35	4 / 328	87%	5.90	154 / 178
spleen	78%	164.73	189 / 241	0%	0	0 / 0
thymus	6%	26.70	40 / 653	69%	6.09	419 / 605
breast	24%	66.60	109 / 459	45%	1.87	502 / 1118
uterus	0%	0	0 / 170	46%	2.48	210 / 459
ovary	0%	0	0 / 180	44%	1.69	191 / 430
peripheral blood	43%	117.35	399 / 929	0%	0	0 / 0
prostate	8%	23.59	19 / 245	34%	0.93	172 / 502
liver	15%	22.58	35 / 226	22%	1.10	88 / 406
brain	19%	55.44	494 / 2642	8%	0.28	58 / 705
eye	0%	0	0 / 0	14%	0.31	11 / 80
adipose	10%	20.13	126 / 1204	0%	0	0 / 0
adrenal gland	3%	8.62	9 / 258	4%	0.13	10 / 230
blood vessel	7%	13.93	96 / 1335	0%	0	0 / 0
heart	1%	1.66	8 / 861	0%	0	0 / 0
muscle	0%	0.26	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0002042	Biological process	cell migration involved in sprouting angiogenesis
GO_0010628	Biological process	positive regulation of gene expression
GO_0003332	Biological process	negative regulation of extracellular matrix constituent secretion
GO_0030195	Biological process	negative regulation of blood coagulation
GO_0071383	Biological process	cellular response to steroid hormone stimulus
GO_1903038	Biological process	negative regulation of leukocyte cell-cell adhesion
GO_0042758	Biological process	long-chain fatty acid catabolic process
GO_0001934	Biological process	positive regulation of protein phosphorylation
GO_0002686	Biological process	negative regulation of leukocyte migration
GO_2000402	Biological process	negative regulation of lymphocyte migration
GO_0050709	Biological process	negative regulation of protein secretion
GO_0140052	Biological process	cellular response to oxidised low-density lipoprotein particle stimulus
GO_0009986	Cellular component	cell surface
GO_0012505	Cellular component	endomembrane system
GO_0005901	Cellular component	caveola
GO_0016020	Cellular component	membrane
GO_0016787	Molecular function	hydrolase activity
GO_0005515	Molecular function	protein binding

Gene name	ADTRP
Protein name	Androgen dependent TFPI regulating protein Androgen-dependent TFPI-regulating protein (Fatty acid esters of hydroxy fatty acids hydrolase ADTRP) (FAHFA hydrolase ADTRP) (EC 3.1.-.-)
Synonyms	C6orf105
Description	FUNCTION: Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids . Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids . Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro) . .
Accessions	ENST00000503285.1 ENST00000229583.9 [Q96IZ2-2] ENST00000414691.8 [Q96IZ2-1] ENST00000379415.6 H0Y9P4 ENST00000505099.5 ENST00000506810.1 H0YAA5 D6R9A9 Q96IZ2 D6RDG9 ENST00000485323.2

ADTRP report