ADAM12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007520Biological processmyoblast fusion
GO_0007155Biological processcell adhesion
GO_0006508Biological processproteolysis
GO_0045766Biological processpositive regulation of angiogenesis
GO_0005654Cellular componentnucleoplasm
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0008237Molecular functionmetallopeptidase activity
GO_0017124Molecular functionSH3 domain binding

IV. Literature review

[source]
Gene nameADAM12
Protein nameADAM metallopeptidase domain 12 (Metalloprotease-disintegrin 12 transmembrane isoform La)
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)
SynonymsMLTN
UNQ346/PRO545
DescriptionFUNCTION: Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity). .

AccessionsENST00000368676.8 [O43184-2]
Q5JRP2
O43184
ENST00000368679.8 [O43184-1]
ENST00000448723.2