Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 31 studies | 29% ± 11% | |
classical monocyte | 24 studies | 38% ± 15% | |
conventional dendritic cell | 22 studies | 28% ± 12% | |
non-classical monocyte | 21 studies | 36% ± 12% | |
monocyte | 20 studies | 30% ± 9% | |
plasmacytoid dendritic cell | 11 studies | 24% ± 6% | |
dendritic cell | 10 studies | 35% ± 15% | |
myeloid cell | 9 studies | 35% ± 13% | |
alveolar macrophage | 7 studies | 21% ± 4% | |
plasma cell | 7 studies | 34% ± 11% | |
mononuclear phagocyte | 5 studies | 32% ± 12% | |
ciliated cell | 5 studies | 25% ± 3% | |
intermediate monocyte | 4 studies | 50% ± 18% | |
plasmablast | 3 studies | 33% ± 13% | |
microglial cell | 3 studies | 22% ± 3% | |
leukocyte | 3 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 8 studies | 22% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 4714.93 | 578 / 578 | 91% | 30.02 | 1050 / 1155 |
breast | 96% | 1863.42 | 440 / 459 | 92% | 26.46 | 1025 / 1118 |
thymus | 98% | 2191.33 | 637 / 653 | 85% | 27.22 | 513 / 605 |
kidney | 93% | 2037.19 | 83 / 89 | 88% | 36.57 | 796 / 901 |
ovary | 82% | 957.16 | 147 / 180 | 94% | 31.44 | 403 / 430 |
prostate | 98% | 1985.62 | 240 / 245 | 77% | 11.81 | 387 / 502 |
brain | 96% | 1515.38 | 2532 / 2642 | 79% | 14.71 | 555 / 705 |
adrenal gland | 97% | 1607.25 | 249 / 258 | 69% | 23.50 | 159 / 230 |
stomach | 85% | 933.57 | 306 / 359 | 76% | 18.88 | 216 / 286 |
intestine | 95% | 2184.96 | 921 / 966 | 61% | 11.83 | 322 / 527 |
esophagus | 83% | 1144.67 | 1197 / 1445 | 73% | 14.67 | 133 / 183 |
bladder | 86% | 1758.10 | 18 / 21 | 69% | 14.35 | 350 / 504 |
uterus | 89% | 1589.14 | 151 / 170 | 65% | 11.98 | 300 / 459 |
pancreas | 64% | 689.47 | 209 / 328 | 86% | 22.57 | 153 / 178 |
skin | 62% | 623.78 | 1117 / 1809 | 80% | 31.51 | 377 / 472 |
spleen | 100% | 12003.22 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 6541.43 | 926 / 929 | 0% | 0 | 0 / 0 |
adipose | 98% | 2253.63 | 1177 / 1204 | 0% | 0 | 0 / 0 |
heart | 97% | 2928.85 | 832 / 861 | 0% | 0 | 0 / 0 |
liver | 39% | 348.41 | 88 / 226 | 58% | 9.66 | 234 / 406 |
lymph node | 0% | 0 | 0 / 0 | 97% | 55.92 | 28 / 29 |
tonsil | 0% | 0 | 0 / 0 | 80% | 24.45 | 36 / 45 |
blood vessel | 73% | 1400.92 | 970 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 53% | 12.03 | 42 / 80 |
muscle | 19% | 127.09 | 151 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0046103 | Biological process | inosine biosynthetic process |
GO_0006154 | Biological process | adenosine catabolic process |
GO_0035578 | Cellular component | azurophil granule lumen |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0008201 | Molecular function | heparin binding |
GO_0043394 | Molecular function | proteoglycan binding |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0046936 | Molecular function | 2'-deoxyadenosine deaminase activity |
GO_0031685 | Molecular function | adenosine receptor binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0008083 | Molecular function | growth factor activity |
GO_0004000 | Molecular function | adenosine deaminase activity |
Gene name | ADA2 |
Protein name | adenosine deaminase (EC 3.5.4.4) Adenosine deaminase 2 (EC 3.5.4.4) (Cat eye syndrome critical region protein 1) Adenosine deaminase 2 |
Synonyms | ADGF CECR1 IDGFL |
Description | FUNCTION: Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. . |
Accessions | ENST00000399839.5 [Q9NZK5-1] B4E3Q4 ENST00000648061.2 A0A087X0I3 A0A3B3IT96 ENST00000696225.1 [Q9NZK5-1] ENST00000649540.1 ENST00000696220.1 A0A3B3IRN1 ENST00000543038.1 A0A8Q3SIK1 ENST00000649310.1 ENST00000696196.1 [Q9NZK5-1] ENST00000696224.1 ENST00000399837.8 [Q9NZK5-1] A0A8Q3WMB0 ENST00000696223.1 ENST00000649915.2 F5H7J3 A0A8Q3SIG4 ENST00000543038.2 [Q9NZK5-1] Q9NZK5 A0A8Q3WM36 ENST00000330232.9 [Q9NZK5-2] ENST00000449907.8 A0A8Q3WL39 ENST00000696197.1 [Q9NZK5-1] ENST00000649746.1 A0A3B3IRR5 ENST00000649746.2 [Q9NZK5-1] ENST00000696227.1 ENST00000262607.3 [Q9NZK5-1] ENST00000696221.1 ENST00000610390.5 ENST00000696226.1 ENST00000649310.2 [Q9NZK5-1] ENST00000696222.1 A0A8Q3WL33 |