ACTR6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006338Biological processchromatin remodeling
GO_0016479Biological processnegative regulation of transcription by RNA polymerase I
GO_0045943Biological processpositive regulation of transcription by RNA polymerase I
GO_0006355Biological processregulation of DNA-templated transcription
GO_0007000Biological processnucleolus organization
GO_0000812Cellular componentSwr1 complex
GO_0005730Cellular componentnucleolus
GO_0005856Cellular componentcytoskeleton
GO_0000786Cellular componentnucleosome
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0031491Molecular functionnucleosome binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameACTR6
Protein nameActin related protein 6
Actin-related protein 6 (hArp6) (hARPX)
ARP6 actin-related protein 6 homolog (Yeast), isoform CRA_d (Actin related protein 6)
SynonymsCDA12
hCG_21802
DescriptionFUNCTION: Required for formation and/or maintenance of proper nucleolar structure and function . Plays a dual role in the regulation of ribosomal DNA (rDNA) transcription (By similarity). In the presence of high glucose, maintains active rDNA transcription through H2A.Z deposition and under glucose starvation, is required for the repression of rDNA transcription, and this function may be independent of H2A.Z (By similarity). .

AccessionsENST00000188312.7 [Q9GZN1-1]
ENST00000551617.1
ENST00000546902.5
Q9GZN1
F8VP72
F8VSD1
G3V1Y1
ENST00000551652.5
F8W043
ENST00000547458.5
F8W0Q1
ENST00000552064.5
F8VRL1
ENST00000553038.5
ENST00000552376.5
F8W057
ENST00000548180.5