Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 15 studies | 44% ± 23% | |
fibroblast | 11 studies | 30% ± 13% | |
adipocyte | 8 studies | 51% ± 16% | |
endothelial cell | 6 studies | 33% ± 13% | |
pericyte | 6 studies | 28% ± 8% | |
type II pneumocyte | 6 studies | 37% ± 13% | |
cardiac muscle cell | 5 studies | 52% ± 14% | |
GABAergic neuron | 3 studies | 37% ± 12% | |
Mueller cell | 3 studies | 35% ± 7% | |
rod bipolar cell | 3 studies | 28% ± 8% | |
hepatocyte | 3 studies | 62% ± 23% | |
smooth muscle cell | 3 studies | 29% ± 9% | |
ependymal cell | 3 studies | 41% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 1972.22 | 89 / 89 | 89% | 11.53 | 801 / 901 |
thymus | 100% | 1732.30 | 653 / 653 | 88% | 6.71 | 532 / 605 |
liver | 100% | 3625.99 | 226 / 226 | 80% | 11.92 | 326 / 406 |
breast | 100% | 2494.63 | 458 / 459 | 66% | 4.38 | 740 / 1118 |
adrenal gland | 100% | 4113.47 | 258 / 258 | 62% | 6.57 | 142 / 230 |
brain | 97% | 1234.50 | 2559 / 2642 | 65% | 4.94 | 455 / 705 |
ovary | 100% | 3415.73 | 180 / 180 | 51% | 2.19 | 220 / 430 |
prostate | 100% | 1390.03 | 244 / 245 | 32% | 1.04 | 162 / 502 |
lung | 99% | 1582.05 | 575 / 578 | 22% | 1.02 | 259 / 1155 |
uterus | 99% | 2673.54 | 169 / 170 | 18% | 1.01 | 84 / 459 |
bladder | 95% | 955.33 | 20 / 21 | 13% | 0.55 | 68 / 504 |
skin | 80% | 633.16 | 1455 / 1809 | 22% | 1.46 | 106 / 472 |
adipose | 100% | 2861.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1507.63 | 1335 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 1557.87 | 830 / 861 | 0% | 0 | 0 / 0 |
muscle | 91% | 651.65 | 730 / 803 | 0% | 0 | 0 / 0 |
pancreas | 56% | 296.32 | 184 / 328 | 29% | 0.77 | 52 / 178 |
intestine | 81% | 639.40 | 779 / 966 | 5% | 0.26 | 24 / 527 |
spleen | 83% | 451.49 | 200 / 241 | 0% | 0 | 0 / 0 |
esophagus | 63% | 417.16 | 917 / 1445 | 4% | 0.25 | 8 / 183 |
eye | 0% | 0 | 0 / 0 | 55% | 2.85 | 44 / 80 |
stomach | 47% | 293.31 | 167 / 359 | 7% | 0.27 | 19 / 286 |
peripheral blood | 2% | 6.91 | 16 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0046951 | Biological process | ketone body biosynthetic process |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0031956 | Molecular function | medium-chain fatty acid-CoA ligase activity |
GO_0003987 | Molecular function | acetate-CoA ligase activity |
GO_0050218 | Molecular function | propionate-CoA ligase activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | ACSS3 |
Protein name | acetate--CoA ligase (EC 6.2.1.1) Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 3) Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 3) (Acyl-CoA synthetase short-chain family member 3) (Propionate--CoA ligase) (EC 6.2.1.17) Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1) (EC 6.2.1.17) (Acetate--CoA ligase 3) (Propionate--CoA ligase) |
Synonyms | hCG_23730 FLJ21963 |
Description | FUNCTION: Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids . Propionate is the preferred substrate . Can utilize acetate and butyrate with a much lower affinity (By similarity). . |
Accessions | A0A0B4J1R2 ENST00000546664.2 H0YII9 F8VZB4 ENST00000548058.6 [Q9H6R3-1] ENST00000261206.7 ENST00000549175.1 Q9H6R3 |