ACR report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ACR at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACR at tissue level.

III. Associated gene sets

GO_0007339Biological processbinding of sperm to zona pellucida
GO_0002077Biological processacrosome matrix dispersal
GO_0007340Biological processacrosome reaction
GO_0007190Biological processactivation of adenylate cyclase activity
GO_0048545Biological processresponse to steroid hormone
GO_0007338Biological processsingle fertilization
GO_0007341Biological processpenetration of zona pellucida
GO_0005576Cellular componentextracellular region
GO_0043159Cellular componentacrosomal matrix
GO_0032991Cellular componentprotein-containing complex
GO_0005634Cellular componentnucleus
GO_0005798Cellular componentGolgi-associated vesicle
GO_0003677Molecular functionDNA binding
GO_0004040Molecular functionamidase activity
GO_0005537Molecular functionD-mannose binding
GO_0002020Molecular functionprotease binding
GO_0042806Molecular functionfucose binding
GO_0008236Molecular functionserine-type peptidase activity
GO_0008270Molecular functionzinc ion binding
GO_0005507Molecular functioncopper ion binding
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameACR
Protein nameAcrosin (EC 3.4.21.10) [Cleaved into: Acrosin light chain; Acrosin heavy chain]
Acrosin
SynonymsACRS
DescriptionFUNCTION: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.

AccessionsE9PLV5
ENST00000529621.1
P10323
ENST00000707314.1
ENST00000216139.10