ACOT7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1900535Biological processpalmitic acid biosynthetic process
GO_0036114Biological processmedium-chain fatty-acyl-CoA catabolic process
GO_0051792Biological processmedium-chain fatty acid biosynthetic process
GO_0015937Biological processcoenzyme A biosynthetic process
GO_0036116Biological processlong-chain fatty-acyl-CoA catabolic process
GO_0009062Biological processfatty acid catabolic process
GO_0006637Biological processacyl-CoA metabolic process
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0052816Molecular functionlong-chain fatty acyl-CoA hydrolase activity
GO_0042803Molecular functionprotein homodimerization activity
GO_0036042Molecular functionlong-chain fatty acyl-CoA binding
GO_0000062Molecular functionfatty-acyl-CoA binding
GO_0005515Molecular functionprotein binding
GO_0052689Molecular functioncarboxylic ester hydrolase activity

IV. Literature review

[source]
Gene nameACOT7
Protein nameAcyl-CoA thioesterase 7
Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Acyl-CoA thioesterase 7) (Brain acyl-CoA hydrolase) (BACH) (hBACH) (CTE-IIa) (CTE-II) (Long chain acyl-CoA thioester hydrolase)
SynonymsBACH
DescriptionFUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels . Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18 . May play an important physiological function in brain . .

AccessionsENST00000377842.7 [O00154-6]
ENST00000418124.5 [O00154-2]
ENST00000473466.2
ENST00000377855.6 [O00154-1]
K7EKP8
ENST00000608083.5 [O00154-4]
ENST00000377845.7 [O00154-5]
ENST00000361521.9 [O00154-7]
O00154
ENST00000377860.8 [O00154-3]