ABRA report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ABRA at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ABRA at tissue level.

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0030036Biological processactin cytoskeleton organization
GO_0006606Biological processprotein import into nucleus
GO_0035025Biological processpositive regulation of Rho protein signal transduction
GO_0051091Biological processpositive regulation of DNA-binding transcription factor activity
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0015629Cellular componentactin cytoskeleton
GO_0030017Cellular componentsarcomere
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameABRA
Protein nameActin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS)
Synonyms
DescriptionFUNCTION: Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. .

AccessionsENST00000311955.4
Q8N0Z2