ABHD17B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1905668Biological processpositive regulation of protein localization to endosome
GO_1902817Biological processnegative regulation of protein localization to microtubule
GO_1902950Biological processregulation of dendritic spine maintenance
GO_1902473Biological processregulation of protein localization to synapse
GO_0002084Biological processprotein depalmitoylation
GO_0099175Biological processregulation of postsynapse organization
GO_0010008Cellular componentendosome membrane
GO_0098839Cellular componentpostsynaptic density membrane
GO_0055038Cellular componentrecycling endosome membrane
GO_0016020Cellular componentmembrane
GO_0005886Cellular componentplasma membrane
GO_0043197Cellular componentdendritic spine
GO_0008474Molecular functionpalmitoyl-(protein) hydrolase activity

IV. Literature review

[source]
Gene nameABHD17B
Protein nameAlpha/beta hydrolase domain-containing protein 17B (Abhydrolase domain-containing protein 17B) (EC 3.1.2.22)
SynonymsFAM108B1
CGI-67
C9orf77
DescriptionFUNCTION: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins . Has depalmitoylating activity towards DLG4/PSD95 . Has depalmitoylating activity towards GAP43 (By similarity). Has depalmitoylating activity towards MAP6 (By similarity). Has depalmitoylating activity towards NRAS . .

AccessionsENST00000377041.6 [Q5VST6-2]
ENST00000333421.7 [Q5VST6-1]
Q5VST6