ABCA5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0055085Biological processtransmembrane transport
GO_0008203Biological processcholesterol metabolic process
GO_0043691Biological processreverse cholesterol transport
GO_0034375Biological processhigh-density lipoprotein particle remodeling
GO_0006869Biological processlipid transport
GO_0010745Biological processnegative regulation of macrophage derived foam cell differentiation
GO_1903064Biological processpositive regulation of reverse cholesterol transport
GO_0010874Biological processregulation of cholesterol efflux
GO_0033344Biological processcholesterol efflux
GO_0042632Biological processcholesterol homeostasis
GO_0031902Cellular componentlate endosome membrane
GO_0005886Cellular componentplasma membrane
GO_0005764Cellular componentlysosome
GO_0000139Cellular componentGolgi membrane
GO_0005770Cellular componentlate endosome
GO_0005765Cellular componentlysosomal membrane
GO_0140359Molecular functionABC-type transporter activity
GO_0005524Molecular functionATP binding
GO_0005319Molecular functionlipid transporter activity
GO_0042626Molecular functionATPase-coupled transmembrane transporter activity
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameABCA5
Protein nameCholesterol transporter ABCA5 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 5)
ABCA5 protein
ATP binding cassette subfamily A member 5
SynonymsDKFZp686K07118
KIAA1888
DescriptionFUNCTION: Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport . May play a role in the processing of autolysosomes (By similarity). .

AccessionsK7EQ50
K7EKS9
ENST00000589975.5
ENST00000591234.5
ENST00000586811.1
ENST00000392676.8 [Q8WWZ7-1]
K7ENF9
ENST00000588665.5
Q8WWZ7
Q6N017
K7EPM3
ENST00000592568.1
A0A075B778
ENST00000593153.5
K7EJW6
K7EMV2
ENST00000586995.5
ENST00000587607.5
ENST00000593253.5
ENST00000588877.5 [Q8WWZ7-1]
Q05C38