Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 15 studies | 27% ± 9% | |
glutamatergic neuron | 11 studies | 52% ± 24% | |
GABAergic neuron | 10 studies | 48% ± 26% | |
oligodendrocyte | 10 studies | 29% ± 11% | |
endothelial cell | 9 studies | 37% ± 19% | |
adipocyte | 8 studies | 50% ± 9% | |
renal alpha-intercalated cell | 7 studies | 53% ± 18% | |
amacrine cell | 7 studies | 42% ± 15% | |
oligodendrocyte precursor cell | 7 studies | 34% ± 14% | |
retinal ganglion cell | 7 studies | 58% ± 23% | |
retinal cone cell | 7 studies | 33% ± 10% | |
retinal rod cell | 7 studies | 31% ± 10% | |
goblet cell | 6 studies | 32% ± 18% | |
interneuron | 6 studies | 51% ± 28% | |
fibroblast | 6 studies | 28% ± 17% | |
basal cell | 6 studies | 32% ± 16% | |
neuron | 5 studies | 30% ± 11% | |
epithelial cell | 5 studies | 44% ± 8% | |
enterocyte | 5 studies | 18% ± 1% | |
retina horizontal cell | 5 studies | 36% ± 20% | |
retinal pigment epithelial cell | 5 studies | 45% ± 11% | |
pericyte | 5 studies | 29% ± 13% | |
Mueller cell | 5 studies | 33% ± 17% | |
retinal bipolar neuron | 4 studies | 41% ± 12% | |
granule cell | 4 studies | 34% ± 11% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 57% ± 15% | |
cardiac muscle cell | 4 studies | 18% ± 2% | |
astrocyte | 4 studies | 37% ± 11% | |
hepatocyte | 4 studies | 53% ± 14% | |
type B pancreatic cell | 3 studies | 41% ± 20% | |
GABAergic interneuron | 3 studies | 48% ± 3% | |
plasma cell | 3 studies | 24% ± 8% | |
mesothelial cell | 3 studies | 20% ± 6% | |
GABAergic amacrine cell | 3 studies | 40% ± 24% | |
OFF-bipolar cell | 3 studies | 43% ± 18% | |
ON-bipolar cell | 3 studies | 45% ± 14% | |
glycinergic amacrine cell | 3 studies | 40% ± 18% | |
rod bipolar cell | 3 studies | 66% ± 17% | |
enteroendocrine cell | 3 studies | 29% ± 11% | |
type I pneumocyte | 3 studies | 22% ± 5% | |
melanocyte | 3 studies | 44% ± 23% | |
kidney loop of Henle epithelial cell | 3 studies | 22% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4026.01 | 245 / 245 | 99% | 8.41 | 498 / 502 |
adrenal gland | 100% | 4092.54 | 258 / 258 | 97% | 10.84 | 223 / 230 |
thymus | 100% | 3344.57 | 652 / 653 | 97% | 6.72 | 586 / 605 |
liver | 100% | 4915.28 | 226 / 226 | 96% | 8.48 | 391 / 406 |
pancreas | 100% | 6197.91 | 328 / 328 | 95% | 6.22 | 169 / 178 |
esophagus | 100% | 2904.47 | 1441 / 1445 | 94% | 6.83 | 172 / 183 |
kidney | 100% | 3339.44 | 89 / 89 | 93% | 6.99 | 837 / 901 |
uterus | 99% | 2453.98 | 168 / 170 | 86% | 5.98 | 396 / 459 |
breast | 100% | 5147.56 | 459 / 459 | 83% | 5.05 | 932 / 1118 |
lung | 98% | 2081.45 | 567 / 578 | 84% | 5.24 | 965 / 1155 |
skin | 95% | 5385.78 | 1718 / 1809 | 85% | 7.11 | 399 / 472 |
bladder | 95% | 2142.71 | 20 / 21 | 81% | 4.95 | 410 / 504 |
stomach | 100% | 2792.10 | 359 / 359 | 76% | 3.72 | 216 / 286 |
intestine | 99% | 3617.17 | 953 / 966 | 76% | 3.92 | 398 / 527 |
brain | 88% | 3276.11 | 2314 / 2642 | 46% | 2.41 | 327 / 705 |
ovary | 99% | 2668.46 | 179 / 180 | 27% | 0.80 | 114 / 430 |
muscle | 100% | 11047.78 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2471.34 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.79 | 1 / 1 |
adipose | 100% | 4220.63 | 1203 / 1204 | 0% | 0 | 0 / 0 |
heart | 91% | 1652.01 | 783 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 89% | 1920.95 | 1190 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 84% | 4.24 | 38 / 45 |
eye | 0% | 0 | 0 / 0 | 64% | 4.16 | 51 / 80 |
lymph node | 0% | 0 | 0 / 0 | 62% | 2.27 | 18 / 29 |
peripheral blood | 24% | 1348.94 | 222 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0055085 | Biological process | transmembrane transport |
GO_0008203 | Biological process | cholesterol metabolic process |
GO_0043691 | Biological process | reverse cholesterol transport |
GO_0034375 | Biological process | high-density lipoprotein particle remodeling |
GO_0006869 | Biological process | lipid transport |
GO_0010745 | Biological process | negative regulation of macrophage derived foam cell differentiation |
GO_1903064 | Biological process | positive regulation of reverse cholesterol transport |
GO_0010874 | Biological process | regulation of cholesterol efflux |
GO_0033344 | Biological process | cholesterol efflux |
GO_0042632 | Biological process | cholesterol homeostasis |
GO_0031902 | Cellular component | late endosome membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005764 | Cellular component | lysosome |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005770 | Cellular component | late endosome |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0140359 | Molecular function | ABC-type transporter activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005319 | Molecular function | lipid transporter activity |
GO_0042626 | Molecular function | ATPase-coupled transmembrane transporter activity |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | ABCA5 |
Protein name | Cholesterol transporter ABCA5 (EC 7.6.2.-) (ATP-binding cassette sub-family A member 5) ABCA5 protein ATP binding cassette subfamily A member 5 |
Synonyms | DKFZp686K07118 KIAA1888 |
Description | FUNCTION: Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport . May play a role in the processing of autolysosomes (By similarity). . |
Accessions | K7EQ50 K7EKS9 ENST00000589975.5 ENST00000591234.5 ENST00000586811.1 ENST00000392676.8 [Q8WWZ7-1] K7ENF9 ENST00000588665.5 Q8WWZ7 Q6N017 K7EPM3 ENST00000592568.1 A0A075B778 ENST00000593153.5 K7EJW6 K7EMV2 ENST00000586995.5 ENST00000587607.5 ENST00000593253.5 ENST00000588877.5 [Q8WWZ7-1] Q05C38 |