Biological process

positive regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity, positive regulation of PGE isomerase activity, positive regulation of PGE2 isomerase activity, positive regulation of PGH-PGE isomerase activity, positive regulation of Prostaglandin-H(2) E-isomerase activity, positive regulation of endoperoxide isomerase activity, positive regulation of prostaglandin H-E isomerase activity, positive regulation of prostaglandin R-prostaglandin E isomerase activity, positive regulation of prostaglandin endoperoxide E isomerase activity, positive regulation of prostaglandin endoperoxide E2 isomerase activity, positive regulation of prostaglandin-H2 E-isomerase activity

Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.