I(KACh) inward rectifier potassium channel complex

I. Literature review

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NameI(KACh) inward rectifier potassium channel complex
IDGO_1990566
collection_id

Cellular component

Description

An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signaling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.

Related synonym

GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex, Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex, muscarinic potassium channel complex

Comment

Examples of this are KCNJ3 and KCNJ5 in human (Uniprot symbols P48549 and P48544) in PMID:9765280 inferred from orthology sequence evidence.

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Genes