histone H4K20 trimethyltransferase activity

I. Literature review

[source]
Namehistone H4K20 trimethyltransferase activity
IDGO_0140943
collection_id

Molecular function

Exact synonym

histone H4K20 trimethylase activity, histone H4K20 trimethylation, histone lysine N-trimethyltransferase activity (H4-K20 specific)

Description

Catalysis of the reaction: L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = 3 H+ + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine. This reaction is the addition of three methyl groups to the lysine residue at position 20 of the histone H4 protein, producing histone H4K20me3.

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Genes