N-terminal protein N-methyltransferase activity

I. Literature review

[source]
NameN-terminal protein N-methyltransferase activity
IDGO_0071885
collection_id

Molecular function

Description

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.

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Genes