Molecular function

Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.

(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity, 15-hydroxy PGD2 dehydrogenase activity, 15-hydroxyprostaglandin dehydrogenase (NADP), NADP-PGD2 dehydrogenase activity, NADP-linked prostaglandin D2 dehydrogenase activity, dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate), dehydrogenase, prostaglandin D2, prostaglandin D2 dehydrogenase activity, prostaglandin-D 15-dehydrogenase (NADP(+)) activity, prostaglandin-D 15-dehydrogenase (NADP), prostaglandin-D 15-dehydrogenase (NADP+) activity