Ku70:Ku80 complex

I. Literature review

[source]
NameKu70:Ku80 complex
IDGO_0043564
collection_id

Cellular component

Exact synonym

Ku70:Ku80 heterodimer

Description

Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.

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Genes