prostaglandin H2 endoperoxidase reductase activity

I. Literature review

[source]
Nameprostaglandin H2 endoperoxidase reductase activity
IDGO_0036130
collection_id

Molecular function

Exact synonym

PGH2 9,11-endoperoxidase, PGH2 9-,11-endoperoxide reductase

Description

Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate).

External URL
Genes
AKR1C3AKR1B1