senescence-associated heterochromatin focus

I. Literature review

[source]
Namesenescence-associated heterochromatin focus
IDGO_0035985
collection_id

Cellular component

Exact synonym

SAHF, senescence-associated heterochromatin foci

Description

A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.

External URL
Genes
HMGA2HMGA1CDKN2A