core-binding factor complex

I. Literature review

[source]
Namecore-binding factor complex
IDGO_0016513
collection_id

Cellular component

Exact synonym

CBF complex

Description

A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.

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Genes