8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity

I. Literature review

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Name8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
IDGO_0008413
collection_id

Molecular function

Exact synonym

7,8-dihydro-8-oxoguanine-triphosphatase activity, 8-oxo-7,8-dihydroguanine triphosphatase activity, 8-oxo-7,8-dihydroguanosine triphosphatase activity, 8-oxo-GTPase activity

Description

Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) + phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.

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Genes