Name | pyrimidine-specific mismatch base pair DNA N-glycosylase activity |
ID | GO_0008263 |
collection_id | Molecular function |
Exact synonym | G/T-mismatch-specific thymine-DNA glycosylase activity |
Description | Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site. |
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Genes |