pyrimidine-specific mismatch base pair DNA N-glycosylase activity

I. Literature review

[source]
Namepyrimidine-specific mismatch base pair DNA N-glycosylase activity
IDGO_0008263
collection_id

Molecular function

Exact synonym

G/T-mismatch-specific thymine-DNA glycosylase activity

Description

Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.

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Genes