B-1 B cell differentiation

I. Literature review

[source]
NameB-1 B cell differentiation
IDGO_0001923
collection_id

Biological process

Exact synonym

B-1 B lymphocyte differentiation, B-1 B-cell differentiation, B-1 B-lymphocyte differentiation

Related synonym

B-1 B cell development

Description

The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.

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Genes