cis assembly of pre-catalytic spliceosome

I. Literature review

[source]
Namecis assembly of pre-catalytic spliceosome
IDGO_0000354
collection_id

Biological process

Alternative ID

GO:0000360, GO:0000361

Description

Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.

Comment

Note that this step represents formation of the A2-1 complex (yeast) or the B1 complex (mammals).

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Genes