Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasmablast | 4 studies | 37% ± 20% | |
| pro-B cell | 4 studies | 24% ± 4% | |
| CD4-positive, alpha-beta T cell | 4 studies | 34% ± 6% | |
| CD8-positive, alpha-beta T cell | 4 studies | 29% ± 6% | |
| B cell | 3 studies | 26% ± 4% | |
| epithelial cell | 3 studies | 32% ± 4% | |
| erythroblast | 3 studies | 40% ± 25% | |
| T cell | 3 studies | 25% ± 8% | |
| transit amplifying cell | 3 studies | 27% ± 6% | |
| natural killer cell | 3 studies | 30% ± 7% |
Insufficient scRNA-seq data for expression of ZWINT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 99% | 1208.04 | 1783 / 1809 | 96% | 50.14 | 455 / 472 |
| breast | 84% | 223.81 | 384 / 459 | 98% | 67.32 | 1092 / 1118 |
| stomach | 76% | 469.79 | 272 / 359 | 99% | 63.90 | 282 / 286 |
| lung | 75% | 295.68 | 431 / 578 | 94% | 58.28 | 1087 / 1155 |
| pancreas | 77% | 151.56 | 254 / 328 | 89% | 28.63 | 159 / 178 |
| intestine | 68% | 546.84 | 654 / 966 | 98% | 72.14 | 518 / 527 |
| bladder | 62% | 157.90 | 13 / 21 | 98% | 72.23 | 495 / 504 |
| thymus | 92% | 241.11 | 599 / 653 | 65% | 23.26 | 396 / 605 |
| ovary | 54% | 122.61 | 97 / 180 | 97% | 44.91 | 418 / 430 |
| esophagus | 51% | 536.35 | 734 / 1445 | 99% | 58.07 | 181 / 183 |
| kidney | 96% | 352.00 | 85 / 89 | 54% | 10.97 | 486 / 901 |
| prostate | 82% | 203.83 | 201 / 245 | 56% | 13.02 | 283 / 502 |
| adrenal gland | 93% | 304.53 | 240 / 258 | 42% | 14.12 | 97 / 230 |
| uterus | 35% | 71.22 | 60 / 170 | 98% | 118.22 | 452 / 459 |
| brain | 65% | 125.35 | 1709 / 2642 | 57% | 19.05 | 405 / 705 |
| liver | 43% | 153.69 | 98 / 226 | 62% | 22.03 | 252 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 94.64 | 29 / 29 |
| spleen | 100% | 757.71 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 117.67 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 41.33 | 1 / 1 |
| adipose | 73% | 166.07 | 874 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 70% | 13.83 | 56 / 80 |
| peripheral blood | 64% | 1700.82 | 596 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 40% | 71.94 | 540 / 1335 | 0% | 0 | 0 / 0 |
| heart | 31% | 51.47 | 267 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 1.84 | 11 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1905325 | Biological process | regulation of meiosis I spindle assembly checkpoint |
| GO_0051301 | Biological process | cell division |
| GO_0007094 | Biological process | mitotic spindle assembly checkpoint signaling |
| GO_0031619 | Biological process | homologous chromosome orientation in meiotic metaphase I |
| GO_0051649 | Biological process | establishment of localization in cell |
| GO_0000070 | Biological process | mitotic sister chromatid segregation |
| GO_0000776 | Cellular component | kinetochore |
| GO_0180019 | Cellular component | Knl1/Spc105 complex |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030425 | Cellular component | dendrite |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ZWINT |
| Protein name | ZW10 interactor (ZW10-interacting protein 1) (Zwint-1) ZW10 interacting kinetochore protein (cDNA FLJ36489 fis, clone THYMU2018126, highly similar to ZW10 interactor) (cDNA FLJ60420, highly similar to ZW10 interactor) ZW10 interacting kinetochore protein |
| Synonyms | |
| Description | FUNCTION: Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase. . |
| Accessions | ENST00000489649.6 ENST00000361148.6 [O95229-2] ENST00000395405.5 [O95229-1] A6NH27 ENST00000318387.6 R4GMS7 ENST00000373944.8 [O95229-1] O95229 |
