ZNF322 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1902459Biological processpositive regulation of stem cell population maintenance
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF322
Protein nameZinc finger protein 322
Zinc finger protein 322 (Zinc finger protein 322A) (Zinc finger protein 388) (Zinc finger protein 489)
SynonymsZNF489
ZNF388
ZNF322A
DescriptionFUNCTION: Transcriptional activator . Important for maintenance of pluripotency in embryonic stem cells (By similarity). Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes (By similarity). Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly (By similarity). Promotes inhibition of MAPK signaling during embryonic stem cell differentiation (By similarity). .

AccessionsENST00000471278.5
ENST00000622479.4
ENST00000480036.5
ENST00000415922.7
ENST00000607204.5
C9JP13
ENST00000456172.5
Q6U7Q0