Insufficient scRNA-seq data for expression of ZCCHC12 at single-cell level.
Insufficient scRNA-seq data for expression of ZCCHC12 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 92% | 3734.97 | 2427 / 2642 | 75% | 12.50 | 529 / 705 |
| uterus | 93% | 6868.52 | 158 / 170 | 23% | 11.74 | 106 / 459 |
| thymus | 29% | 327.80 | 189 / 653 | 81% | 856.98 | 489 / 605 |
| adrenal gland | 21% | 105.36 | 55 / 258 | 71% | 57.72 | 163 / 230 |
| ovary | 42% | 262.62 | 76 / 180 | 23% | 3.73 | 98 / 430 |
| stomach | 13% | 73.39 | 46 / 359 | 6% | 0.26 | 16 / 286 |
| intestine | 13% | 38.84 | 125 / 966 | 3% | 0.18 | 18 / 527 |
| lung | 6% | 35.87 | 33 / 578 | 10% | 1.16 | 117 / 1155 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 1.53 | 3 / 29 |
| pancreas | 0% | 0 | 0 / 328 | 9% | 0.74 | 16 / 178 |
| breast | 5% | 19.01 | 24 / 459 | 2% | 0.17 | 23 / 1118 |
| bladder | 0% | 0 | 0 / 21 | 7% | 0.63 | 36 / 504 |
| skin | 0% | 2.54 | 5 / 1809 | 6% | 1.25 | 29 / 472 |
| esophagus | 3% | 9.52 | 39 / 1445 | 3% | 0.63 | 6 / 183 |
| prostate | 2% | 4.85 | 4 / 245 | 4% | 0.19 | 20 / 502 |
| liver | 0% | 2.59 | 1 / 226 | 4% | 0.30 | 18 / 406 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.18 | 2 / 80 |
| blood vessel | 1% | 5.97 | 19 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 1% | 4.30 | 13 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 1% | 2.98 | 2 / 241 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.03 | 7 / 901 |
| muscle | 0% | 0.48 | 1 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.31 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005634 | Cellular component | nucleus |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0003676 | Molecular function | nucleic acid binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ZCCHC12 |
| Protein name | Zinc finger CCHC domain-containing protein 12 (Smad-interacting zinc finger protein 1) |
| Synonyms | SIZN1 |
| Description | FUNCTION: Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity). . |
| Accessions | ENST00000310164.3 Q6PEW1 |