ZC3HC1 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	3 studies	30% ± 10%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	22% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	861.31	89 / 89	100%	31.60	901 / 901
liver	100%	747.87	226 / 226	100%	16.16	406 / 406
ovary	100%	766.41	180 / 180	100%	18.14	430 / 430
thymus	100%	757.89	653 / 653	100%	18.01	605 / 605
uterus	100%	926.61	170 / 170	100%	22.31	459 / 459
prostate	100%	842.02	245 / 245	100%	15.84	501 / 502
skin	100%	768.06	1807 / 1809	100%	35.72	471 / 472
breast	100%	822.57	459 / 459	100%	19.45	1114 / 1118
esophagus	100%	723.53	1439 / 1445	100%	12.63	183 / 183
adrenal gland	100%	1104.79	258 / 258	100%	18.94	229 / 230
brain	99%	598.01	2628 / 2642	100%	29.73	705 / 705
bladder	100%	837.00	21 / 21	99%	17.24	501 / 504
stomach	100%	634.01	358 / 359	100%	12.98	285 / 286
intestine	100%	777.46	963 / 966	99%	14.16	523 / 527
pancreas	99%	394.20	324 / 328	99%	14.09	177 / 178
lung	95%	566.75	549 / 578	100%	17.40	1155 / 1155
eye	0%	0	0 / 0	100%	19.56	80 / 80
lymph node	0%	0	0 / 0	100%	28.82	29 / 29
muscle	100%	1453.40	803 / 803	0%	0	0 / 0
spleen	100%	1187.74	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	16.52	45 / 45
ureter	0%	0	0 / 0	100%	10.12	1 / 1
adipose	100%	778.46	1203 / 1204	0%	0	0 / 0
blood vessel	100%	636.80	1332 / 1335	0%	0	0 / 0
heart	100%	829.20	857 / 861	0%	0	0 / 0
peripheral blood	78%	474.33	728 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0016567	Biological process	protein ubiquitination
GO_2001240	Biological process	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO_0051301	Biological process	cell division
GO_0005654	Cellular component	nucleoplasm
GO_0031965	Cellular component	nuclear membrane
GO_0005634	Cellular component	nucleus
GO_0019901	Molecular function	protein kinase binding
GO_0005515	Molecular function	protein binding
GO_0008270	Molecular function	zinc ion binding

Gene name	ZC3HC1
Protein name	Zinc finger C3HC-type protein 1 (Nuclear-interacting partner of ALK) (hNIPA) (Nuclear-interacting partner of anaplastic lymphoma kinase) Zinc finger C3HC-type containing 1 ZC3HC1 protein
Synonyms	HSPC216 NIPA
Description	FUNCTION: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events. .
Accessions	ENST00000467642.5 Q86WB0 ENST00000484432.1 F8WF13 ENST00000358303.9 [Q86WB0-1] ENST00000648450.1 ENST00000360708.9 [Q86WB0-3] F8WAU5 F8WBD7 ENST00000483827.1 C9J0I9 ENST00000481503.5 ENST00000311873.9 [Q86WB0-2] ENST00000470651.1 F8WDK5 Q9BWJ8

ZC3HC1 report