ZACN report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZACN at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZACN at tissue level.

III. Associated gene sets

GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0010043Biological processresponse to zinc ion
GO_0098655Biological processmonoatomic cation transmembrane transport
GO_1902495Cellular componenttransmembrane transporter complex
GO_0005886Cellular componentplasma membrane
GO_0004888Molecular functiontransmembrane signaling receptor activity
GO_0160128Molecular functionpH-gated monoatomic ion channel activity
GO_0005230Molecular functionextracellular ligand-gated monoatomic ion channel activity
GO_0099094Molecular functionligand-gated monoatomic cation channel activity
GO_0015276Molecular functionligand-gated monoatomic ion channel activity
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameZACN
Protein nameLigand-gated cation channel ZACN (Ligand-gated ion channel zinc-activated 1) (Ligand-gated ion-channel receptor L2) (Zinc-activated channel)
SynonymsLGICZ
L2
LGICZ1
ZAC
DescriptionFUNCTION: Ligand-gated cation channel that allows the movement of sodium and potassium monoatomic cations across cell membranes when activated by zinc (Zn2+), copper (Cu2+), and changes in pH . Could also transport cesium . .

AccessionsENST00000334586.10 [Q401N2-1]
Q401N2
ENST00000425015.5 [Q401N2-2]
ENST00000421794.1 [Q401N2-3]