XYLT2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of XYLT2 at tissue level.

III. Associated gene sets

GO_0050650Biological processchondroitin sulfate proteoglycan biosynthetic process
GO_0030203Biological processglycosaminoglycan metabolic process
GO_0015012Biological processheparan sulfate proteoglycan biosynthetic process
GO_0030206Biological processchondroitin sulfate biosynthetic process
GO_0030210Biological processheparin biosynthetic process
GO_0006024Biological processglycosaminoglycan biosynthetic process
GO_0005615Cellular componentextracellular space
GO_0000139Cellular componentGolgi membrane
GO_0030145Molecular functionmanganese ion binding
GO_0000287Molecular functionmagnesium ion binding
GO_0030158Molecular functionprotein xylosyltransferase activity

IV. Literature review

[source]
Gene nameXYLT2
Protein nameXylosyltransferase 2 (EC 2.4.2.26) (Xylosyltransferase II)
Xylosyltransferase 2 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase II) (XT-II) (XylT-II)
Xylosyltransferase 2
SynonymsXT2
UNQ3058/PRO9878
hCG_29612
DescriptionFUNCTION: Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. .

AccessionsENST00000509778.1
I3L3K2
B4DT06
ENST00000376550.7
Q9H1B5
D6RCT0
H0YB00
ENST00000574840.1
ENST00000017003.7 [Q9H1B5-1]
A0A0C4DFW8
ENST00000511654.1
ENST00000507602.5