XPNPEP3 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	13 studies	24% ± 9%	Explore
astrocyte	6 studies	30% ± 11%	Explore
epithelial cell	5 studies	25% ± 6%	Explore
oligodendrocyte	5 studies	24% ± 5%	Explore
endothelial cell	4 studies	23% ± 4%	Explore
glutamatergic neuron	4 studies	40% ± 14%	Explore
GABAergic neuron	3 studies	38% ± 8%	Explore
oligodendrocyte precursor cell	3 studies	27% ± 6%	Explore
ependymal cell	3 studies	29% ± 9%	Explore
adipocyte	3 studies	22% ± 0%	Explore

Name	Number of supported studies	Average coverage
brain	5 studies	33% ± 10%	Explore
liver	3 studies	23% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1005.07	1445 / 1445	100%	12.39	183 / 183
stomach	100%	895.13	359 / 359	100%	9.07	286 / 286
breast	100%	1264.63	459 / 459	100%	10.15	1117 / 1118
intestine	100%	989.58	966 / 966	100%	7.75	526 / 527
prostate	100%	1287.56	245 / 245	100%	7.56	501 / 502
brain	100%	842.58	2634 / 2642	100%	7.21	705 / 705
bladder	100%	1085.52	21 / 21	99%	7.30	501 / 504
kidney	100%	1409.28	89 / 89	99%	7.84	895 / 901
lung	99%	1135.36	575 / 578	100%	9.15	1151 / 1155
uterus	100%	1238.36	170 / 170	99%	6.76	455 / 459
ovary	100%	1651.63	180 / 180	99%	6.42	426 / 430
liver	100%	1720.00	226 / 226	99%	6.99	401 / 406
skin	100%	1589.48	1809 / 1809	98%	8.52	464 / 472
pancreas	100%	881.90	327 / 328	98%	5.76	175 / 178
adrenal gland	100%	2043.90	258 / 258	98%	6.72	225 / 230
thymus	100%	1609.30	653 / 653	97%	5.15	588 / 605
adipose	100%	1210.08	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	6.03	29 / 29
spleen	100%	1253.65	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	6.66	45 / 45
ureter	0%	0	0 / 0	100%	4.69	1 / 1
blood vessel	100%	775.71	1334 / 1335	0%	0	0 / 0
muscle	100%	813.10	801 / 803	0%	0	0 / 0
heart	99%	1280.97	854 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	5.09	77 / 80
peripheral blood	74%	520.01	686 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0016485	Biological process	protein processing
GO_0006508	Biological process	proteolysis
GO_0003094	Biological process	glomerular filtration
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005739	Cellular component	mitochondrion
GO_0030145	Molecular function	manganese ion binding
GO_0042803	Molecular function	protein homodimerization activity
GO_0005515	Molecular function	protein binding
GO_0070006	Molecular function	metalloaminopeptidase activity
GO_0004177	Molecular function	aminopeptidase activity

Gene name	XPNPEP3
Protein name	X-prolyl aminopeptidase 3 Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3)
Synonyms	hCG_41117 LOC63929
Description	FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala . Also shows low activity towards peptides with Ala or Ser at the P1 position . .; FUNCTION: [Isoform 1]: Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling. .
Accessions	F2Z316 Q9NQH7 ENST00000614001.1 ENST00000428799.1 A0A087X0Z2 ENST00000357137.9 [Q9NQH7-1]

XPNPEP3 report