XAGE3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
extravillous trophoblast	3 studies	78% ± 10%	Explore
placental villous trophoblast	3 studies	91% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
placenta	3 studies	62% ± 26%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	73%	4.32	166 / 226	15%	0.31	62 / 406
breast	57%	7.20	263 / 459	1%	0.70	11 / 1118
adipose	56%	3.51	671 / 1204	0%	0	0 / 0
kidney	43%	1.71	38 / 89	2%	0.07	22 / 901
lung	32%	1.14	183 / 578	6%	1.10	67 / 1155
stomach	24%	0.66	87 / 359	2%	0.03	5 / 286
skin	11%	0.26	197 / 1809	11%	3.74	51 / 472
pancreas	19%	0.48	62 / 328	2%	0.30	3 / 178
brain	16%	0.42	424 / 2642	0%	0	0 / 705
muscle	15%	0.38	124 / 803	0%	0	0 / 0
ovary	4%	0.09	7 / 180	9%	1.11	37 / 430
thymus	10%	0.27	66 / 653	0%	0.01	3 / 605
intestine	8%	0.18	75 / 966	1%	0.04	6 / 527
uterus	5%	0.12	9 / 170	3%	1.19	15 / 459
bladder	5%	0.10	1 / 21	2%	0.19	11 / 504
blood vessel	6%	0.19	74 / 1335	0%	0	0 / 0
prostate	4%	0.09	11 / 245	0%	0	0 / 502
adrenal gland	4%	0.10	11 / 258	0%	0	0 / 230
eye	0%	0	0 / 0	4%	0.06	3 / 80
esophagus	4%	0.08	51 / 1445	0%	0	0 / 183
heart	3%	0.07	25 / 861	0%	0	0 / 0
peripheral blood	2%	0.03	14 / 929	0%	0	0 / 0
spleen	1%	0.02	2 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1