XAGE2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
extravillous trophoblast	3 studies	90% ± 8%	Explore
placental villous trophoblast	3 studies	95% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
placenta	3 studies	64% ± 28%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	86%	51.62	497 / 578	26%	8.18	297 / 1155
ovary	2%	0.29	3 / 180	48%	12.28	208 / 430
skin	34%	3.56	614 / 1809	11%	1.73	51 / 472
kidney	43%	3.49	38 / 89	1%	0.09	5 / 901
adipose	28%	2.86	341 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	21%	4.73	17 / 80
breast	14%	1.34	66 / 459	5%	4.85	54 / 1118
uterus	6%	0.28	10 / 170	10%	4.61	46 / 459
pancreas	8%	0.40	27 / 328	3%	2.10	5 / 178
stomach	4%	0.17	13 / 359	6%	0.96	18 / 286
intestine	4%	0.17	34 / 966	5%	1.00	26 / 527
bladder	0%	0	0 / 21	8%	5.27	40 / 504
esophagus	3%	0.13	46 / 1445	4%	0.23	7 / 183
blood vessel	5%	0.29	66 / 1335	0%	0	0 / 0
liver	2%	0.08	4 / 226	2%	2.11	10 / 406
brain	4%	0.17	100 / 2642	0%	0.01	1 / 705
prostate	4%	0.18	9 / 245	0%	0	0 / 502
thymus	1%	0.05	7 / 653	0%	0	0 / 605
peripheral blood	1%	0.04	8 / 929	0%	0	0 / 0
spleen	1%	0.03	2 / 241	0%	0	0 / 0
muscle	1%	0.03	6 / 803	0%	0	0 / 0
adrenal gland	0%	0.01	1 / 258	0%	0	0 / 230
heart	0%	0.15	3 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1