WDR3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030490Biological processmaturation of SSU-rRNA
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0034388Cellular componentPwp2p-containing subcomplex of 90S preribosome
GO_0005654Cellular componentnucleoplasm
GO_0031965Cellular componentnuclear membrane
GO_0032040Cellular componentsmall-subunit processome
GO_0030515Molecular functionsnoRNA binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameWDR3
Protein nameWD repeat domain 3, isoform CRA_b (cDNA FLJ77605, highly similar to Homo sapiens WD repeat domain 3 (WDR3), mRNA)
WD repeat-containing protein 3
WD repeat domain 3 (WDR3 protein)
SynonymshCG_37073
DescriptionFUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. .

AccessionsQ5TDG3
Q9UNX4
ENST00000369441.7
Q6PDA5
ENST00000349139.6