Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 41 studies | 44% ± 16% | |
microglial cell | 11 studies | 31% ± 19% | |
myeloid cell | 11 studies | 34% ± 10% | |
conventional dendritic cell | 9 studies | 29% ± 8% | |
alveolar macrophage | 8 studies | 66% ± 20% | |
monocyte | 7 studies | 38% ± 17% | |
dendritic cell | 5 studies | 31% ± 14% | |
mononuclear phagocyte | 5 studies | 35% ± 10% | |
classical monocyte | 5 studies | 25% ± 5% | |
leukocyte | 3 studies | 26% ± 9% | |
non-classical monocyte | 3 studies | 26% ± 1% | |
tissue-resident macrophage | 3 studies | 58% ± 8% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 5 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 97% | 9279.37 | 560 / 578 | 85% | 53.96 | 982 / 1155 |
breast | 80% | 3563.71 | 366 / 459 | 80% | 25.64 | 893 / 1118 |
adrenal gland | 92% | 5418.60 | 237 / 258 | 53% | 18.28 | 121 / 230 |
bladder | 90% | 2386.86 | 19 / 21 | 54% | 26.44 | 272 / 504 |
intestine | 85% | 2984.91 | 821 / 966 | 52% | 17.09 | 276 / 527 |
ovary | 46% | 925.93 | 83 / 180 | 83% | 41.03 | 357 / 430 |
brain | 20% | 355.72 | 524 / 2642 | 97% | 149.44 | 686 / 705 |
pancreas | 30% | 495.33 | 98 / 328 | 85% | 46.87 | 152 / 178 |
stomach | 53% | 1453.30 | 192 / 359 | 62% | 18.31 | 176 / 286 |
kidney | 34% | 1177.18 | 30 / 89 | 81% | 43.88 | 729 / 901 |
thymus | 46% | 936.36 | 303 / 653 | 67% | 16.40 | 407 / 605 |
skin | 25% | 439.17 | 460 / 1809 | 81% | 43.32 | 384 / 472 |
esophagus | 61% | 2183.60 | 877 / 1445 | 46% | 11.27 | 84 / 183 |
uterus | 46% | 966.90 | 79 / 170 | 50% | 16.35 | 229 / 459 |
adipose | 96% | 9423.23 | 1154 / 1204 | 0% | 0 | 0 / 0 |
spleen | 85% | 5566.07 | 206 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 76% | 3662.87 | 1014 / 1335 | 0% | 0 | 0 / 0 |
prostate | 44% | 769.19 | 108 / 245 | 28% | 4.33 | 141 / 502 |
liver | 31% | 669.51 | 71 / 226 | 34% | 9.24 | 139 / 406 |
lymph node | 0% | 0 | 0 / 0 | 62% | 91.39 | 18 / 29 |
heart | 53% | 1379.57 | 456 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 51% | 3116.43 | 472 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 47% | 12.11 | 21 / 45 |
eye | 0% | 0 | 0 / 0 | 38% | 8.85 | 30 / 80 |
muscle | 16% | 223.74 | 126 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043031 | Biological process | negative regulation of macrophage activation |
GO_0006957 | Biological process | complement activation, alternative pathway |
GO_0045957 | Biological process | negative regulation of complement activation, alternative pathway |
GO_0042130 | Biological process | negative regulation of T cell proliferation |
GO_0032703 | Biological process | negative regulation of interleukin-2 production |
GO_0032991 | Cellular component | protein-containing complex |
GO_0016020 | Cellular component | membrane |
GO_0001851 | Molecular function | complement component C3b binding |
GO_0005515 | Molecular function | protein binding |
Gene name | VSIG4 |
Protein name | V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig) V-set and immunoglobulin domain containing 4 |
Synonyms | CRIg UNQ317/PRO362 Z39IG |
Description | FUNCTION: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. . |
Accessions | ENST00000427538.5 Q9Y279 ENST00000412866.2 [Q9Y279-3] ENST00000651578.1 ENST00000455586.6 [Q9Y279-2] ENST00000374737.9 [Q9Y279-1] H7C062 A0A494C0F5 |