VSIG4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043031Biological processnegative regulation of macrophage activation
GO_0006957Biological processcomplement activation, alternative pathway
GO_0045957Biological processnegative regulation of complement activation, alternative pathway
GO_0042130Biological processnegative regulation of T cell proliferation
GO_0032703Biological processnegative regulation of interleukin-2 production
GO_0032991Cellular componentprotein-containing complex
GO_0016020Cellular componentmembrane
GO_0001851Molecular functioncomplement component C3b binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameVSIG4
Protein nameV-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig)
V-set and immunoglobulin domain containing 4
SynonymsCRIg
UNQ317/PRO362
Z39IG
DescriptionFUNCTION: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. .

AccessionsENST00000427538.5
Q9Y279
ENST00000412866.2 [Q9Y279-3]
ENST00000651578.1
ENST00000455586.6 [Q9Y279-2]
ENST00000374737.9 [Q9Y279-1]
H7C062
A0A494C0F5