VSIG2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
epithelial cell	11 studies	32% ± 14%	Explore
goblet cell	9 studies	30% ± 9%	Explore
type I pneumocyte	8 studies	38% ± 14%	Explore
secretory cell	7 studies	27% ± 8%	Explore
club cell	6 studies	33% ± 7%	Explore
respiratory goblet cell	6 studies	42% ± 16%	Explore
squamous epithelial cell	4 studies	41% ± 21%	Explore
type II pneumocyte	4 studies	25% ± 7%	Explore
ciliated cell	4 studies	19% ± 4%	Explore
basal cell	3 studies	28% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
intestine	3 studies	22% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	2682.14	651 / 653	84%	98.33	506 / 605
prostate	97%	1956.87	237 / 245	76%	78.86	383 / 502
bladder	100%	3186.38	21 / 21	71%	199.66	358 / 504
stomach	84%	13671.69	302 / 359	66%	65.70	189 / 286
lung	100%	1769.21	577 / 578	49%	41.07	567 / 1155
intestine	46%	1894.56	449 / 966	64%	76.27	337 / 527
ureter	0%	0	0 / 0	100%	384.40	1 / 1
kidney	90%	325.18	80 / 89	10%	9.38	86 / 901
breast	78%	378.23	359 / 459	21%	10.67	235 / 1118
pancreas	8%	26.43	27 / 328	90%	203.87	161 / 178
esophagus	49%	440.19	711 / 1445	36%	41.85	66 / 183
uterus	54%	188.22	92 / 170	27%	25.78	123 / 459
blood vessel	57%	157.69	764 / 1335	0%	0	0 / 0
adipose	57%	219.12	684 / 1204	0%	0	0 / 0
ovary	10%	28.23	18 / 180	37%	20.87	158 / 430
heart	44%	114.92	379 / 861	0%	0	0 / 0
liver	14%	36.27	32 / 226	13%	8.55	54 / 406
spleen	24%	55.59	58 / 241	0%	0	0 / 0
peripheral blood	22%	57.84	208 / 929	0%	0	0 / 0
adrenal gland	5%	10.63	13 / 258	15%	9.22	35 / 230
brain	10%	19.76	257 / 2642	0%	0.07	3 / 705
skin	7%	15.76	135 / 1809	1%	0.34	5 / 472
tonsil	0%	0	0 / 0	4%	0.94	2 / 45
muscle	1%	1.91	8 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0